Auto-injector
An auto-injector comprising an elongate housing containing a syringe. The housing having an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring pushing the needle from a covered position into an advanced position, operating the syringe and covering the needle. An activator arranged to lock the spring prior to manual operation and capable of, upon manual operation, releasing the spring means for injection. A first gear arrangement and a second gear arrangement arranged fro converting torque from a first end and a second end of the torsion spring into a translative force. The first end groundable in the housing while the second end acts on a plunger through the second gear arrangement for advancing the needle and supplying the dose.
1 . A method comprising:
removing a cap from a proximal end of an auto-injector while a lip defined by a distal end of a plunger remains engaged to a first part of the auto-injector to hold the plunger in a fixed axial position within the auto-injector and a proximal end of the plunger is disposed within a distal portion of a syringe, wherein an axial portion of the plunger connecting the lip of the plunger to the proximal end of the plunger is substantially centered on a longitudinal axis of the auto-injector;
after removing the cap, radially deflecting the lip of the plunger out of engagement with the first part of the auto-injector to release the plunger from being held in the fixed axial position within the auto-injector such that the plunger moves proximally within the auto-injector along the longitudinal axis of the auto-injector and the proximal end of the plunger proximally displaces a stopper within the syringe to (i) insert a needle of the syringe into an injection site and (ii) inject a medicament from the syringe into the injection site; and
after injecting at least a portion of the medicament from the syringe and before injecting all of the medicament from the syringe, initiating a rotation of a second part relative to the plunger about the longitudinal axis of the auto-injector by a rotational biasing force of a torsion spring, wherein the second part is disposed radially outward of the plunger as the plunger proximally moves within the auto-injector,
wherein the auto-injector is configured such that no further medicament is injected into the injection site after the second part has completed the rotation within the auto-injector.
2 . The method of claim 1 , wherein, in an as-delivered state, the plunger is held in the fixed axial position within the auto-injector by the engagement between the lip and the first part of the auto-injector.
3 . The method of claim 1 , wherein the lip extends radially outward from the plunger and a proximally-facing surface of the lip is engaged to a distally-facing surface of the first part of the auto-injector to hold the plunger in the fixed axial position within the auto-injector prior to the lip radially deflecting out of engagement with the first part of the auto-injector.
4 . The method of claim 1 , comprising depressing a button located at a distal end of the auto-injector in a proximal direction to radially deflect the lip of the plunger out of engagement with the first part of the auto-injector to release the plunger from being held in the fixed axial position within the auto-injector.
5 . The method of claim 4 , comprising proximally moving a proximally-extending portion of the button relative to the lip of the plunger as the button is depressed, the proximally-extending portion of the button extending from a radially-inward portion of a proximal surface of the button.
6 . The method of claim 5 , wherein the proximally-extending portion of the button is disposed radially outward of the lip of the plunger, and an axial length of the proximally-extending portion is less than an entire axial length of the button.
7 . The method of claim 5 , comprising moving a third part relative to the button to allow the button to be depressed such that a duration of time between moving the third part relative to the button, depressing the button, and injecting the medicament can be within 10 seconds.
8 . The method of claim 1 , comprising limiting the rotation of the plunger within the auto-injector as the plunger proximally moves within the auto-injector by a non-cylindrical pin that extends axially within the auto-injector.
9 . The method of claim 1 , comprising producing an audible indication to indicate that the medicament has been dispensed.