COMPOSITIONS AND METHODS FOR TREATING EYES AND METHODS OF PREPARATION
Pharmaceutical compositions, methods for treating various issues of the eyes, and methods of preparing such compositions are described. These pharmaceutical compositions may be for treating glaucoma, in preparation of eye surgery, during eye surgery, various post-op care (e.g., after cataract surgery, laser eye surgery, and the like), for treating dry eyes, and/or for promoting eyelash growth. These pharmaceutical compositions may comprise such active ingredients (APIs) as: timolol, latanoprost, brimonidine tartrate, dorzolamide, moxifloxacin HCl, dexamethasone PO 4 , phenylephrine HCl, lidocaine HCl, ketorolac tromethamine, bromfenac, prednisolone PO 4 , gatifloxacin, amniotic cytokine extract (ACE), prostaglandin E2 (PGE2), and combinations thereof.
1 . A pharmaceutical composition comprising: phenylephrine HCl, lidocaine HCl, and ketorolac tromethamine.
2 . The pharmaceutical composition of claim 1 , wherein the pharmaceutical composition
comprises: phenylephrine HCl 1.5%, lidocaine HCl 1%, and ketorolac tromethamine 0.3%, wherein these percentages are with respect to weight per volume.
3 . The pharmaceutical composition of claim 2 , further comprising an isotonic buffer.
4 . The pharmaceutical composition of claim 2 , further comprising sodium chloride
5 . The pharmaceutical composition of claim 2 , wherein the pharmaceutical composition has a pH of about 6.5.
6 . The pharmaceutical composition of claim 2 , wherein the pharmaceutical composition is preservative-free.
7 . A pharmaceutical composition comprising: phenylephrine HCl, lidocaine HCl, and bromfenac.
8 . The pharmaceutical composition of claim 7 , wherein the pharmaceutical composition comprises: phenylephrine HCl 1.5%, lidocaine HCl 1%, and bromfenac at 0.01%.
9 . The pharmaceutical composition of claim 7 , wherein the pharmaceutical composition comprises: phenylephrine HCl 1.5%, lidocaine HCl 1%, and bromfenac at 0.07%.
10 . The pharmaceutical composition of claim 7 , further comprising an isotonic buffer.
11 . The pharmaceutical composition of claim 7 , further comprising sodium chloride.
12 . The pharmaceutical composition of claim 7 , wherein the pharmaceutical composition has a pH of 7.0 to 7.2.
13 . The pharmaceutical composition of claim 7 , wherein the pharmaceutical composition is preservative-free.
14 . A delivery device comprising a pharmaceutical composition comprising:
phenylephrine HCl, lidocaine HCl, and ketorolac tromethamine.
15 . The delivery device of claim 14 , wherein the pharmaceutical composition comprises: phenylephrine HCl 1.5%, lidocaine HCl 1%, and ketorolac tromethamine 0.3%, wherein these percentages are with respect to weight per volume.
16 . A method for treating an ocular condition of an eye; comprising administering the pharmaceutical composition of claim 1 at, in, or around the eye via a delivery device and per a predetermined dosing regimen.
17 . The method of claim 16 , wherein the pharmaceutical composition comprises: phenylephrine HCl 1.5%, lidocaine HCl 1%, and ketorolac tromethamine 0.3%, and wherein these percentages are with respect to weight per volume.
18 . The method of claim 16 , wherein the pharmaceutical composition is preservative-free.