IP Library › Granted Patent US 12,516,964
Granted Patent B2
US 12,516,964 · App. 19/037,440 · Granted Jan 6, 2026

Method and apparatus for breath-hold monitoring in diagnostic and therapeutic procedures

Inventor: Manojeet Bhattacharya (Edina, MN)
Assignee: EmpNia Inc.
G01D5/35316A41D13/1281A61B5/6804G01D5/35335G01D5/35367G01L1/246G02B6/022
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Quick Facts
Patent No.
US 12,516,964
App. No.
19/037,440
Granted
Jan 6, 2026
Kind
B2
Abstract

A method for compensating for dynamic changes in a body of a patient during a controlled interaction with the body includes acquiring data from at least one sensing device disposed on the body and detecting a change along at least one optical fiber of the sensing device caused by dynamic changes associated with the body during the controlled interaction. A respiratory gating signal is generated based on the change along the at least one optical fiber of the sensing device measured over time. The method further comprises controlling relative movement between the body and an interactive device in response to the respiratory gating signal to compensate for the dynamic changes associated with the body during the controlled interaction.

Claims (51)

1 . A method of compensating for dynamic changes in a body of a patient during an image-guided interaction with a target region of the body, the method comprising:

acquiring data from an optical fiber-based sensing device disposed on the body, the data representing a change along at least one optical fiber of the sensing device caused by dynamic changes associated with the body during the image-guided interaction;

determining a position of the target region of the body based on the change along the at least one optical fiber of the sensing device;

controlling a scanning device, based on the change along the at least one optical fiber of the sensing device caused by the dynamic changes associated with the body, to acquire image data of the target region of the body during the dynamic changes; and

controlling an interactive device, based on the determined position of the target region, to compensate for the dynamic changes during the image-guided interaction by limiting relative movement between the target region of the body and the interactive device.

2 . The method of claim 1 , wherein the sensing device comprises at least one fiber Bragg grating (FBG).

3 . The method of claim 2 , wherein:

the acquiring data from the optical fiber-based sensing device comprises acquiring wavelength data from the at least one FBG, the change along the at least one optical fiber of the sensing device comprises effective shifts of Bragg wavelengths in the wavelength data; and

the determining the position of the target region comprises determining the position of the target region based on the effective shifts of the Bragg wavelengths.

4 . The method of claim 3 , wherein the

controlling the scanning device based on the change along the at least one optical fiber of the sensing device comprises controlling the scanning device based on the effective shifts of the Bragg wavelengths in the wavelength data caused by the dynamic changes during the image-guided interaction.

5 . The method of claim 4 , wherein the controlling the interactive device comprises controlling the interactive device, based at least in part on the determined position and the acquired image data, to perform the image-guided interaction with the target region while compensating for the dynamic changes.

6 . The method of claim 1 , wherein the dynamic changes associated with the body include at least one of body deformation, respiratory motion, tumor motion, or organ motion.

7 . The method of claim 1 , wherein the image-guided interaction is at least one of an external beam treatment, a focused energy treatment procedure, a biopsy procedure, or a guided placement of an interventional device.

8 . The method of claim 7 , wherein the external beam treatment is external beam radiotherapy or proton beam therapy.

9 . A method of compensating for dynamic changes in a body of a patient during an image-guided interaction with a target region of the body, the method comprising:

acquiring data from an optical fiber-based sensing device disposed on the body, the data representing a change along at least one optical fiber of the sensing device caused by dynamic changes associated with the body during the image-guided interaction;

determining a change in a position of the target region of the body based on the change along the at least one optical fiber of the sensing device;

controlling a scanning device, based on the change along the at least one optical fiber of the sensing device caused by the dynamic changes associated with the body, to acquire image data of the target region of the body during the dynamic changes; and

controlling an interactive device, based on the change in the position of the target region and the acquired image data, to limit relative movement between the target region of the body and the interactive device caused by the dynamic changes during the image-guided interaction.

10 . The method of claim 9 , wherein the optical fiber-based sensing device comprises at least one fiber Bragg grating (FBG).

11 . The method of claim 10 , wherein:

the acquiring data from the optical fiber-based sensing device comprises acquiring wavelength data from the at least one FBG, the change along the at least one optical fiber of the sensing device comprises effective shifts of Bragg wavelengths in the wavelength data; and

the determining the change in the position of the target region comprises determining the change in the position of the target region based on the effective shifts of the Bragg wavelengths.

12 . The method of claim 11 , wherein the image-guided interaction is an image-guided interaction with the target region of the body, the

controlling the scanning device based on the change along the at least one optical fiber of the sensing device comprises controlling the scanning device, based on the effective shifts of the Bragg wavelengths in the wavelength data caused by the dynamic changes during the image-guided interaction.

13 . The method of claim 12 , wherein the controlling the interactive device comprises controlling the interactive device to perform the image-guided interaction with the target region while compensating for the dynamic changes.

14 . The method of claim 9 , wherein the dynamic changes associated with the body include at least one of body deformation, respiratory motion, tumor motion, or organ motion.

15 . The method of claim 9 , wherein the image-guided interaction is at least one of an external beam treatment, a focused energy treatment procedure, a biopsy procedure, or a guided placement of an interventional device.

16 . The method of claim 15 , wherein the external beam treatment is external beam radiotherapy or proton beam therapy.

17 . A method of compensating for dynamic changes in a body of a patient during an image-guided interaction with a target region of the body, the method comprising:

acquiring wavelength data from at least one fiber Bragg grating (FBG) disposed on the body;

determining a position of the target region of the body based on effective shifts of Bragg wavelengths in the wavelength data caused by dynamic changes associated with the body during the image-guided interaction;

controlling a scanning device, based on the effective shifts of the Bragg wavelengths in the wavelength data caused by the dynamic changes during the image-guided interaction, to acquire image data of the target region of the body during the dynamic changes; and

controlling an interactive device, based on the determined position and the acquired image data, to limit relative movement between the target region of the body and the interactive device.

18 . The method of claim 17 , wherein the dynamic changes associated with the body include at least one of body deformation, respiratory motion, tumor motion, or organ motion.

19 . The method of claim 17 , wherein the controlling the interactive device comprises controlling the interactive device to perform the image-guided interaction with the target region while compensating for the dynamic changes.

20 . The method of claim 17 , wherein the image-guided interaction is an image-guided therapeutic interaction.

21 . The method of claim 17 , wherein the image-guided interaction is an image-guided therapeutic interaction, the therapeutic interaction including at least one of an external beam treatment, a focused energy treatment procedure, a biopsy procedure, or a guided placement of an interventional device.

22 . The method of claim 21 , wherein the external beam treatment is external beam radiotherapy or proton beam therapy.

23 . A method of compensating for dynamic changes in a body of a patient during an image-guided interaction with a target region of the body, the method comprising:

acquiring wavelength data from at least one fiber Bragg gratings (FBG) disposed on a body;

controlling a scanning device, based on effective shifts of Bragg wavelengths in the wavelength data caused by the dynamic changes associated with the body during the image-guided interaction, to acquire image data of the target region of the body during the dynamic changes; and

controlling an interactive device, based at least in part on the acquired image data, to perform the image-guided interaction with the target region while compensating for the dynamic changes.

24 . The method of claim 23 , wherein the dynamic changes associated with the body include at least one of body deformation, respiratory motion, tumor motion, or organ motion.

25 . The method of claim 23 , wherein the image-guided interaction is an image-guided interaction with the target region of the body.

26 . The method of claim 19 , further comprising:

determining a change in a position of the target region of the body based on the effective shifts of the Bragg wavelengths in the wavelength data caused by dynamic changes associated with the body during the image-guided interaction with the target region.

27 . The method of claim 26 , wherein the controlling the interactive device comprises controlling the interactive device, based at least in part on the change in position and the acquired image data, to perform the image-guided interaction with the target region while compensating for the dynamic changes.

28 . The method of claim 23 , wherein the image-guided interaction is a therapeutic interaction, the therapeutic interaction including at least one of an external beam treatment, a focused energy treatment procedure, a biopsy procedure, or a guided placement of an interventional device.

29 . The method of claim 28 , wherein the external beam treatment is external beam radiotherapy or proton beam therapy.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 30, 2025
From: BHATTACHARYA, MANOJEET
To: EMPNIA INC.
Reel/Frame 070056/0713 →
Continuity (6)
Continuation 18900208 · Sep 27, 2024
Continuation In Part 18409081 · Jan 10, 2024
Continuation 17224855 · Apr 7, 2021
Continuation In Part PCTUS2020065691 · Dec 17, 2020
Continuation In Part 16723352 · Dec 20, 2019
Related Publication 20250172415A1 · May 29, 2025
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