IP Library Granted Patent US 12,551,502
Granted Patent B1
US 12,551,502 · App. 19/094,018 · Granted Feb 17, 2026

Testosterone enhancing compositions and methods

Inventor: Natalie Jones (Charlotte, NC)
Assignee: Direct Digital
A61K33/30A61K31/198A61K31/4415A61K31/593A61K31/69A61K31/714A61K35/10A61K36/31A61K36/45A61K36/5777A61K36/736A61K36/742A61K36/82A61K36/9066A61P5/26A61P25/00
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,551,502
App. No.
19/094,018
Granted
Feb 17, 2026
Kind
B1
Abstract

The present invention is a nutraceutical, and method of administering it, to create both a rapid increase in free and total testosterone in the bloodstream as well as modulation of sleep cycles to a PSQI score of 5 or lower, including the key ingredients of 1 mg zinc (chelated or zinc citrate); 1125 mg L-Citrulline Malate (2:1); 400 mg Tesnor® (Pomegranate peel and cocoa bean extracts); 150 mg of elevATP®, an adenosine triphosphate (ATP) stimulating composition containing peat extract and apple fruit extract; 100-150 mg Tongkat Ali ( Eurycoma longifolia ) root extract, and 10 mg boron as boron glycinate, together with one or more excipients. The combination of these ingredients, together with optional Vitamin B6, Vitamin B12, and Vitamin D, and optional 25 mg of S7® (green coffee extract (bean), green tea extract (leaf), turmeric extract (rhizome), sour cherry (fruit), blueberry (fruit), broccoli (flower), and kale (leaf)) gives new and unexpectedly improved results over any of the constituents administered alone or in any other combination.

Claims (6)

1 . A method for simultaneously modulating sleep cycles and increasing free and total testosterone in the blood in a human in need of such dual treatment, consisting essentially of the steps of: compounding a capsule containing a) 1 mg zinc selected from the group consisting of zinc citrate and chelated zinc; b) 1125 mg citrulline maleate; c) 400 mg pomegranate peel and cocoa bean extracts; d) 150 mg of an adenosine triphosphate stimulating composition containing peat extract and apple fruit extract; 3) 150 mg Eurycoma longifolia extract and 10 mg boron glycinate, together with one or more pharmaceutically acceptable excipients, and dosing said human with a dosing protocol of administering three of said capsules per day to said human for a plurality of days and realizing both free and total testosterone increase and beneficial sleep cycle modulation over said plurality of days.

2 . The method according to claim 1 , wherein the step of compounding in a capsule includes the further addition of f) 2 mg Vitamin B6 and 2.4 micrograms of Vitamin B12.

3 . The method according to claim 1 , wherein the step of compounding a capsule includes the further addition of 20 mcg Vitamin D and 25 mg of a combination of green coffee bean extract, green tea leaf extract, turmeric rhizome extract, sour cherry fruit, blueberry fruit, broccoli flower, and kale leaf, and wherein said plurality of days is between 28 and 56 days.

4 . The method of claim 1 , wherein said monitoring step includes confirming that modulation of sleep cycles conforms to a score of 5 or lower on the Pittsburgh Sleep Quality Index.

5 . A capsule product obtained by the method of claim 1 .

6 . The capsule product according to claim 5 wherein said capsule product is a gelatin capsule product.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 28, 2025
From: JONES, NATALIE, MS.
To: DIRECT DIGITAL LLC D/B/A ADAPTIVE HEALTH
Reel/Frame 070665/0234 →
References Cited (13)
US 10668097B1 · Jones · 2020 [cited by examiner]
WO WO2019215755A2 · 2019 [cited by applicant]
Henkel et al. (Phytother. Res. 28: 544-550 (2014)) (Year: 2014). [cited by examiner]
Nemzer et al. (Free Radical Research 2017; DOI: 10.1080/10715762.2017.1390228; 12 pages) (Year: 2017). [cited by examiner]
Pandit et al. (Int. J. Med. Sci. 2022;19:1290-1299) (Year: 2022). [cited by examiner]
Bruno, G. (Nutritional Outlook [online] retrieved on May 12, 25 from: https://www.nutritionaloutlook.com/view/men-s-sexual-health-supporting-testosterone-and-nitric-oxide-production-with-nutraceuticals; 2021:7 pages) (Y… [cited by examiner]
Pattnaik et al. (Dec. 21, 2022) Nutritional Elements in Sleep. Cureus 14(12):9 pages). (Year: 2022). [cited by examiner]
Ahmad et al. (Trop J Nat Prod Res. 2023;7(5):3002-3008) (Year: 2023). [cited by examiner]
Toyama et al. (Abstract of: Jpn Pharmacol Ther. 2022;50:871-6; 2 pages). (Year: 2022). [cited by examiner]
Srivastava, Manoj et al., “A combination of Punica Granatum . . . ,” Int. J. Med Sci., vol. 22, pp. 383-397 (2025). [cited by applicant]
Pandit, S. L et al., “A proprietary blend of standardized . . . ,” Int. J. Med. Sci., vol. 13, pp. 1290-1299 (2022). [cited by applicant]
Sreeramaneni, P. et al., “A proprietary herbal blend containing . . . ,” Journal of Dietary Supplements, vol. 20, No. 4 pp. 1-17 (2022). [cited by applicant]
Steels, E et al., “Physiological Aspects . . . ,” Phytotherapy Research, John Wiley & Sons, 2011. [cited by applicant]