IP Library Patent Application 19226007
Patent Application
App. No. 19/226,007

TWO-LEAD QT INTERVAL PREDICTION

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Quick Facts
Patent No.
US None
App. No.
19/226,007
Abstract

Embodiments of the present disclosure provide a mobile electrocardiogram (ECG) sensor comprising an electrode assembly comprising electrodes, wherein the electrode assembly senses heart-related signals when in contact with a body of a user, and produces electrical signals representing the sensed heart-related signals. The ECG sensor further comprises a processing device, operatively coupled to the electrode assembly, the processing device to provide the sensed heart-related signals to a machine learning module trained to predict a twelve-lead QT interval (QTc) value from the mobile ECG sensor comprising less than twelve leads. The ECG sensor also comprises a housing containing the electrode assembly and the processing device.

Claims (56)

1 . (canceled)

2 . An apparatus comprising:

an electrode assembly configured to produce signals representing electrical activity of a user's heart; and

a processing device, operatively coupled to the electrode assembly, the processing device configured to:

train a machine learning (ML) model by:

for each of a plurality of training electrocardiogram (ECG) measurements:

analyzing, using the ML model, the training ECG measurement to generate an output;

comparing the output to a corresponding QT interval label to generate an error that is based the output and the corresponding QT interval label; and

updating the ML model based on the error;

provide the signals representing the electrical activity of the user's heart to the ML model to predict a twelve-lead QT interval (QTc) value based on the signals; and

analyze, using the ML model, the predicted QTc value to determine whether a health anomaly is present.

3 . The apparatus of claim 2 , wherein for each of the plurality of training ECG

measurements:

the processing device generates the error using a loss function that is based on a cross entropy term of the output, the corresponding QT interval label, and a root mean squared QT interval average.

4 . The apparatus of claim 2 , wherein the signals correspond to an ECG measurement that is less than 12 leads.

5 . The apparatus of claim 2 , wherein the plurality of training ECG measurements are from a single user so that the ML model is trained to predict the twelve-lead QTc value for the single user.

6 . The apparatus of claim 2 , wherein the ML model is a deep neural network ML model.

7 . The apparatus of claim 2 , wherein the signals comprise Lead I and Lead II signals.

8 . The apparatus of claim 2 , wherein to analyze the predicted QTc value to determine whether a health anomaly is present, the processing device analyzes the predicted QTc value to determine whether QTc prolongation is present.

9 . The apparatus of claim 2 , wherein the processing device is further to send a notification to a device of the user in response to determining that the health anomaly is present.

10 . A method comprising:

generating signals representing electrical activity of a user's heart;

training a machine learning (ML) model by:

for each of a plurality of training electrocardiogram (ECG) measurements:

analyzing, using the ML model, the training ECG measurement to generate an output;

comparing the output to a corresponding QT interval label to generate an error that is based the output and the corresponding QT interval label; and

updating the ML model based on the error;

providing the signals representing the electrical activity of the user's heart to the ML model to predict a twelve-lead QT interval (QTc) value based on the signals; and

analyze, using the ML model, the predicted QTc value to determine whether a health anomaly is present.

11 . The method of claim 10 , wherein for each of the plurality of training ECG

measurements:

the error is generated using a loss function that is based on a cross entropy term of the output, the corresponding QT interval label, and a root mean squared QT interval average.

12 . The method of claim 10 , wherein the signals correspond to an ECG measurement that is less than 12 leads.

13 . The method of claim 10 , wherein the plurality of training ECG measurements are from a single user so that the ML model is trained to predict the twelve-lead QTc value for the single user.

14 . The method of claim 10 , wherein the ML model is a deep neural network ML model.

15 . The method of claim 10 , wherein the signals comprise Lead I and Lead II signals.

16 . The method of claim 15 , wherein analyzing the predicted QTc value to determine whether a health anomaly is present comprises analyzing the predicted QTc value to determine whether QTc prolongation is present.

17 . The method of claim 15 , wherein further comprising sending a notification to a device of the user in response to determining that the health anomaly is present.

18 . A system comprising:

a user device; and

a monitoring device comprising:

an electrode assembly configured to produce signals representing electrical activity of a user's heart; and

a processing device, operatively coupled to the electrode assembly, the processing device configured to:

train a machine learning (ML) model by:

for each of a plurality of training electrocardiogram (ECG) measurements:

 analyzing, using the ML model, the training ECG measurement to generate an output;

 comparing the output to a corresponding QT interval label to generate an error that is based the output and the corresponding QT interval label; and

 updating the ML model based on the error;

provide the signals representing the electrical activity of the user's heart to the ML model to predict a twelve-lead QT interval (QTc) value based on the signals;

analyze, using the ML model, the predicted QTc value to determine whether a health anomaly is present; and

send a notification to the user device in response to determining that the health anomaly is present.

19 . The system of claim 18 , wherein for each of the plurality of training ECG

measurements:

the processing device generates the error using a loss function that is based on a cross entropy term of the output, the corresponding QT interval label, and a root mean squared QT interval average.

20 . The system of claim 18 , wherein the signals correspond to an ECG measurement that is less than 12 leads.

21 . The system of claim 18 , wherein the plurality of training ECG measurements are from a single user so that the ML model is trained to predict the twelve-lead QTc value for the single user.

Assignments (2)
SECURITY INTEREST Recorded Jun 24, 2026
From: ALIVECOR, INC.
To: SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT
Reel/Frame 075813/0343 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2025
From: SCHRAM, MATTHEW
To: ALIVECOR, INC.
Reel/Frame 073092/0418 →