IP Library › Patent Application 19242394
Patent Application
App. No. 19/242,394

CRYSTALLINE FORM OF TRIETHYLENETETRAMINE TETRAHYDROCHLORIDE AND ITS PHARMACEUTICAL USE

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Quick Facts
Patent No.
US None
App. No.
19/242,394
Abstract

The present invention describes a new crystalline form of triethylenetetramine tetrachloride which has improved room temperature stability over known forms and over the dichloride salt. The new crystalline form is characterised by having peaks in an XRPD spectrum at 22.9, 25.4, 25.8, 26.6, 34.6 and 35.3±0.1° 2θ and Raman shifts 943, 1173, 1527 and 1612±5 cm −1 . The crystalline form of triethylenetetramine tetrachloride is useful in the treatment of Wilson's disease.

Claims (3)

1 . A crystalline form of triethylenetetramine tetrachloride having at least one of the following characteristics:

(i) an XRPD pattern having at least two peaks selected from the peaks at 22.9, 25.4, 25.8, 26.6, 34.6 and 35.3±0.1° 2Q; and/or

(ii) (ii) a Raman spectrum having at least two peaks selected from the peaks at a Raman shift of 943, 1173, 1527 and 1612±5 cm −1 .

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE CONVEYING PARTY DATA NAME AND RECEIVING PARTY DATA PREVIOUSLY RECORDED ON REEL 72989 FRAME 799. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME. Recorded May 1, 2026
From: GMP-ORPHAN SA
To: ORPHALAN SA
Reel/Frame 076104/0631 →
CHANGE OF NAME Recorded Oct 2, 2025
From: GMP-ORPHAN
To: ORPHALAN
Reel/Frame 072989/0799 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 2, 2025
From: MORLEY, TIMOTHY JAMES; LAWRENCE, RONNIE MAXWELL; AMIN, NASEEM
To: GMP-ORPHAN SA
Reel/Frame 073004/0835 →