IP Library Granted Patent US 7,050,848
Granted Patent B2
US 7,050,848 · App. 10/812,038 · Granted May 23, 2006

Tissue discrimination and applications in medical procedures

Assignee: NuVasive, Inc.
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Quick Facts
Patent No.
US 7,050,848
App. No.
10/812,038
Filed
Mar 29, 2004
Granted
May 23, 2006
Kind
B2
Art Unit
3736
USPC
600/547
Abstract

A system and method for discriminating tissue types, controlling the level of therapy to tissue, and determining the health or a known tissue by measuring the characteristics an electrical signal applied to conductive element located within or by the tissue. Additionally, the system and method may be used for determining whether the conductive tip of a pedicle probe or pedicle screw is located in one of cortical bone, cancellous bone, and cortical bone near a boundary with soft tissue, whether the conductive tip of a cannula is located adjacent to one of nerve tissue and annulus tissue, and whether the conductive tip of a cathode is located adjacent to one of nerve tissue and prostate gland tissue.

Claims (33)

1. A method of identifying a characterized body tissue located adjacent to a conductive element of a probe comprising the steps of:

a) applying an electrical signal to the conductive element;

b) determining characteristics of the applied signal, including a phase angle; and

c) identifying a type of characterized body tissue located adjacent to the conductive element of a probe based on the phase angle of the applied signal, wherein said characterized body tissue comprises at least one of cortical bone and cancellous bone.

2. The method of claim 1 , wherein the determined characteristics of the applied signal include an impedance of the signal through the tissue.

3. The method of claim 1 , wherein the probe comprises one of a cannula and a cathode.

4. The method of claim 1 , wherein step a) applies signals having a range of predetermined frequencies to the conductive element.

5. The method of claim 1 , wherein step c) includes identifying the characterized body tissue located adjacent to the conductive element of said probe based on the determined characteristics and frequency of the resulting signal.

6. The method of claim 1 , wherein the conductive element is an electrode.

7. The method of claim 1 , wherein the conductive element includes a pair of electrodes and the signal is passed between said electrodes.

8. The method of claim 1 , wherein the signal is an electrical signal having a sliding frequency.

9. An article of manufacture for use in identifying a characterized body tissue located adjacent to a conductive element of a probe, the article of manufacture comprising computer readable storage media including program logic embedded therein that causes control circuitry to perform the steps of:

a) applying a signal to the conductive element;

b) determining characteristics of the applied signal, including a phase angle; and

c) identifying a type of characterized body tissue located adjacent to the conductive element of a probe based on the phase angle of the applied signal, wherein said characterized body tissue comprises at least one of cortical bone and cancellous bone.

10. The article of manufacture of claim 9 , wherein the determined characteristics of the applied signal further include an impedance of the signal through the tissue.

11. The article of manufacture of claim 9 , wherein the probe comprises one of a cannula and a cathode.

12. The article of manufacture of claim 9 , wherein step a) applies signals having a range of predetermined frequencies to the conductive element.

13. The article of manufacture of claim 9 , wherein step c) includes identifying the characterized body tissue located adjacent to the conductive element of said probe based on the determined characteristics and frequency of the resulting signal.

14. The article of manufacture of claim 9 , wherein the conductive element is an electrode.

15. The article of manufacture of claim 9 , wherein the conductive element includes a pair of electrodes and the signal is passed between said electrodes.

16. The article of manufacture of claim 9 , wherein the signal is an electrical signal having a sliding frequency.

17. An apparatus for use in identifying a characterized body tissue located adjacent to a conductive element of a probe, the apparatus including:

a) means for applying a signal to the conductive element;

b) means for determining characteristics of the applied signal, including a phase angle of the signal; and

c) means for identifying a type of characterized body tissue located adjacent to the conductive element of a probe based on the phase angle of the applied signal, wherein said characterized body tissue comprises at least one of cortical bone and cancellous bone.

18. The apparatus of claim 17 , wherein the determined characteristics of the applied signal include an impedance of the signal through the tissue.

19. The apparatus of claim 17 , wherein the probe comprises one of a cannula and a cathode.

20. The apparatus of claim 17 , wherein means for applying a signal includes means for applying signals having a range of predetermined frequencies to the conductive element.

21. The apparatus of claim 17 , wherein the means for identifying said tissue located adjacent to the conductive element of said probe includes means for determining whether the conductive element of a probe is located adjacent to said tissue based on the determined characteristics and frequency of the signal.

22. The apparatus of claim 17 , wherein the conductive element is an electrode.

23. The apparatus of claim 17 , wherein the conductive element includes a pair of electrodes and the signal is passed between said electrodes.

24. The apparatus of claim 17 , wherein the signal is an electrical signal having a sliding frequency.

Assignments (4)
SECURITY INTEREST Recorded Feb 28, 2020
From: NUVASIVE, INC.; NUVASIVE CLINICAL SERVICES MONITORING, INC.; NUVASIVE CLINICAL SERVICES, INC.; NUVASIVE SPECIALIZED ORTHOPEDICS, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 052918/0595 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded May 17, 2017
From: NUVASIVE, INC.; BIOTRONIC NATIONAL, LLC; NUVASIVE CLINICAL SERVICES MONITORING, INC.; NUVASIVE CLINICAL SERVICES, INC.; NUVASIVE SPECIALIZED ORTHOPEDICS, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 042490/0236 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Nov 16, 2016
From: NUVASIVE, INC.; IMPULSE MONITORING, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 040634/0404 →
CHANGE OF ADDRESS Recorded May 20, 2009
From: NUVASIVE, INC.
To: NUVASIVE, INC.
Reel/Frame 022706/0920 →
Continuity (4)
Division 0986064800 · May 18, 2001
Provisional Application 6024346500 · Oct 25, 2000
Provisional Application 6020563400 · May 18, 2000
Related Publication 20040181165A1 · Sep 16, 2004