IP Library Granted Patent US 7,332,602
Granted Patent B2
US 7,332,602 · App. 11/561,991 · Granted Feb 19, 2008

Pyridyl substituted heterocycles useful for treating or preventing HCV infection

Assignee: Rigel Pharmaceuticals, Inc.
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Quick Facts
Patent No.
US 7,332,602
App. No.
11/561,991
Granted
Feb 19, 2008
Kind
B2
Abstract

The present invention relates to pyridyl substituted heterocycles and hydro isomers thereof and pharmaceutical compositions thereof that inhibit replication and/or proliferation of HCV virus. The present invention also relates to the use of the pyridyl heterocycles and hydro isomers thereof and/or pharmaceutical compositions comprising the compounds to treat or prevent HCV infections.

Claims (54)

1. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

2. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

3. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

4. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

5. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

6. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

7. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

8. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

9. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

10. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

11. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

12. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

13. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

14. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

15. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

16. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

17. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

18. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

19. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

20. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

21. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

22. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

23. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

24. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

25. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

26. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

27. A compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

Assignments (2)
SECURITY INTEREST Recorded Aug 25, 2022
From: RIGEL PHARMACEUTICALS, INC.
To: MIDCAP FINANCIAL TRUST
Reel/Frame 061327/0712 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2007
From: SINGH, RAJINDER; GOFF, DANE; PARTRIDGE, JOHN; LU, HENRY H
To: RIGEL PHARMACEUTICALS, INC.
Reel/Frame 018873/0198 →
Continuity (5)
Continuation 1064634800 · Aug 22, 2003
Provisional Application 6047137300 · May 15, 2003
Provisional Application 6041783700 · Oct 11, 2002
Provisional Application 6040546700 · Aug 23, 2002
Related Publication 20070155966A1 · Jul 5, 2007