IP Library › Granted Patent US 7,368,527
Granted Patent B2
US 7,368,527 · App. 10/105,299 · Granted May 6, 2008

HADDE71 polypeptides

Assignee: Human Genome Sciences, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,368,527
App. No.
10/105,299
Granted
May 6, 2008
Kind
B2
Abstract

The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to said human secreted proteins. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.

Claims (28)

1. An isolated polypeptide comprising amino acid residues 29 to 139 of SEQ ID NO:3118.

2. The isolated polypeptide of claim 1 which comprises amino acid residues 2 to 139 of SEQ ID NO:3118.

3. The isolated polypeptide of claim 1 which comprises amino acid residues 1 to 139 of SEQ ID NO:3118.

4. The polypeptide of claim 1 which further comprises a heterologous polypeptide sequence.

5. A composition comprising the polypeptide of claim 1 and a carrier.

6. An isolated protein produced by the method comprising:

(a) expressing the polypeptide of claim 1 by a cell; and

(b) recovering said protein.

7. An isolated polypeptide comprising the amino acid sequence of the secreted portion of the polypeptide encoded by the HADDE71 cDNA contained in ATCC Deposit No. 203917.

8. The isolated polypeptide of claim 7 which comprises the amino acid sequence of the complete polypeptide encoded by the HADDE71 cDNA contained in ATCC Deposit No. 203917, excepting the N-terminal methionine.

9. The isolated polypeptide of claim 7 which comprises the amino acid sequence of the complete polypeptide encoded by the HADDE71 cDNA contained in ATCC Deposit No. 203917.

10. The polypeptide of claim 7 which further comprises a heterologous polypeptide sequence.

11. A composition comprising the polypeptide of claim 7 and a carrier.

12. An isolated protein produced by the method comprising:

(a) expressing the protein of claim 7 by a cell; and

(b) recovering said protein.

13. An isolated polypeptide consisting of at least 30 contiguous amino acid residues of amino acid residues 1 to 139 of SEQ ID:3118, wherein said polypeptide comprises amino acid residues 1-20, 21-40, 41-60, 61-80, or 81-100 of SEQ ID:3118.

14. The polypeptide of claim 13 which further comprises a heterologous polypeptide sequence.

15. A composition comprising the polypeptide of claim 13 and a carrier.

16. An isolated protein produced by the method comprising:

(a) expressing the polypeptide of claim 13 by a cell; and

(b) recovering said protein.

17. An isolated polypeptide consisting of at least 30 contiguous amino acid residues of the complete polypeptide encoded by the HADDE71 cDNA clone in ATCC Deposit No. 203917, wherein said polypeptide comprises amino acid residues 1-20, 21-40, 41-60, 61-80, or 81-100 of the HADDE71 cDNA clone in ATCC Deposit No. 203917.

18. The polypeptide of claim 17 which further comprises a heterologous polypeptide sequence.

19. A composition comprising the polypeptide of claim 17 and a carrier.

20. An isolated protein produced by the method comprising:

(a) expressing the polypeptide of claim 17 by a cell; and

(b) recovering said protein.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 26, 2002
From: ROSEN, CRAIG A.; RUBEN, STEVEN M.
To: HUMAN GENOME SCIENCES, INC.
Reel/Frame 012744/0818 →
Continuity (185)
Continuation In Part 0995008200 · Sep 12, 2001
Continuation In Part 0995008300 · Sep 12, 2001
Continuation In Part PCTUS011331800 · Apr 27, 2001
Continuation In Part PCTUS002633700 · Sep 26, 2000
Continuation In Part PCTUS002632300 · Sep 26, 2000
Continuation In Part PCTUS002632400 · Sep 26, 2004
Continuation In Part PCTUS002637100 · Sep 26, 2004
Continuation In Part PCTUS002637600 · Sep 26, 2004
Continuation In Part PCTUS001496400 · Jun 1, 2000
Continuation In Part PCTUS001497300 · Jun 1, 2000
Continuation In Part PCTUS001492800 · Jun 1, 2000
Continuation In Part PCTUS001513700 · Jun 1, 2000
Continuation In Part PCTUS001493300 · Jun 1, 2000
Continuation In Part PCTUS001493400 · Jun 1, 2000
Continuation In Part PCTUS001513500 · Jun 1, 2000
Continuation In Part PCTUS001496300 · Jun 1, 2000
Continuation In Part PCTUS001492600 · Jun 1, 2000
Continuation In Part PCTUS001513600 · Jun 1, 2000
Continuation In Part PCTUS001492900 · Jun 1, 2000
Continuation In Part PCTUS000906900 · Apr 6, 2000
Continuation In Part PCTUS000907100 · Apr 6, 2000
Continuation In Part PCTUS000898000 · Apr 6, 2000
Continuation In Part PCTUS000898100 · Apr 6, 2000
Continuation In Part PCTUS000906800 · Apr 6, 2000
Continuation In Part PCTUS000906600 · Apr 6, 2000
Continuation In Part PCTUS000906700 · Apr 6, 2000
Continuation In Part PCTUS000898300 · Apr 6, 2000
Continuation In Part PCTUS000898200 · Apr 6, 2000
Continuation In Part PCTUS000907000 · Apr 6, 2000
Continuation In Part PCTUS000772500 · Mar 23, 2000
Continuation In Part PCTUS000767700 · Mar 23, 2000
Continuation In Part PCTUS000772600 · Mar 23, 2000
Continuation In Part PCTUS000757800 · Mar 23, 2000
Continuation In Part PCTUS000772200 · Mar 23, 2000
Continuation In Part PCTUS000772400 · Mar 23, 2000
Continuation In Part PCTUS000772300 · Mar 23, 2000
Continuation In Part PCTUS000757900 · Mar 23, 2000
Continuation In Part PCTUS000766100 · Mar 23, 2000
Continuation In Part PCTUS000752700 · Mar 22, 2000
Continuation In Part PCTUS000752600 · Mar 22, 2000
Continuation In Part PCTUS000748300 · Mar 22, 2000
Continuation In Part PCTUS000753400 · Mar 22, 2000
Continuation In Part PCTUS000752500 · Mar 22, 2000
Continuation In Part PCTUS000753500 · Mar 22, 2000
Continuation In Part PCTUS000750700 · Mar 22, 2000
Continuation In Part PCTUS000750600 · Mar 22, 2000
Continuation In Part PCTUS000744000 · Mar 22, 2000
Continuation In Part PCTUS000750500 · Mar 22, 2000
Continuation In Part PCTUS000678100 · Mar 16, 2000
Continuation In Part PCTUS000682300 · Mar 16, 2000
Continuation In Part PCTUS000682800 · Mar 16, 2000
Continuation In Part PCTUS000679100 · Mar 16, 2000
Continuation In Part PCTUS000682200 · Mar 16, 2000
Continuation In Part PCTUS000678200 · Mar 16, 2000
Continuation In Part PCTUS000683000 · Mar 16, 2000
Continuation In Part PCTUS000679200 · Mar 16, 2000
Continuation In Part PCTUS000676500 · Mar 16, 2000
Continuation In Part PCTUS000682400 · Mar 16, 2000
Continuation In Part PCTUS000605700 · Mar 9, 2000
Continuation In Part PCTUS000604900 · Mar 9, 2000
Continuation In Part PCTUS000601300 · Mar 9, 2000
Continuation In Part PCTUS000601400 · Mar 9, 2000
Continuation In Part PCTUS000604200 · Mar 9, 2000
Continuation In Part PCTUS000605900 · Mar 9, 2000
Continuation In Part PCTUS000604400 · Mar 9, 2000
Continuation In Part PCTUS000605800 · Mar 9, 2000
Continuation In Part PCTUS000601200 · Mar 9, 2000
Continuation In Part PCTUS000604300 · Mar 9, 2000
Provisional Application 6027865000 · Mar 27, 2001
Provisional Application 6021214200 · Jun 16, 2000
Provisional Application 6020119400 · May 2, 2000
Provisional Application 6017693100 · Jan 20, 2000
Provisional Application 6017693000 · Jan 20, 2000
Provisional Application 6017692900 · Jan 20, 2000
Provisional Application 6017692600 · Jan 20, 2000
Provisional Application 6017716600 · Jan 20, 2000
Provisional Application 6017705000 · Jan 20, 2000
Provisional Application 6017704900 · Jan 20, 2000
Provisional Application 6017606900 · Jan 14, 2000
Provisional Application 6017606800 · Jan 14, 2000
Provisional Application 6017606400 · Jan 14, 2000
Provisional Application 6017606300 · Jan 14, 2000
Provisional Application 6017605200 · Jan 14, 2000
Provisional Application 6017487700 · Jan 7, 2000
Provisional Application 6017487200 · Jan 7, 2000
Provisional Application 6017487100 · Jan 7, 2000
Provisional Application 6017485200 · Jan 7, 2000
Provisional Application 6017485100 · Jan 7, 2000
Provisional Application 6017485000 · Jan 7, 2000
Provisional Application 6017150400 · Dec 22, 1999
Provisional Application 6017154900 · Dec 22, 1999
Provisional Application 6017155000 · Dec 22, 1999
Provisional Application 6017155100 · Dec 22, 1999
Provisional Application 6017155200 · Dec 22, 1999
Provisional Application 6017240800 · Dec 17, 1999
Provisional Application 6017240900 · Dec 17, 1999
Provisional Application 6017241000 · Dec 17, 1999
Provisional Application 6017241200 · Dec 17, 1999
Provisional Application 6017241300 · Dec 17, 1999
Provisional Application 6016990600 · Dec 10, 1999
Provisional Application 6016991000 · Dec 10, 1999
Provisional Application 6016993600 · Dec 10, 1999
Provisional Application 6016991600 · Dec 10, 1999
Provisional Application 6016994600 · Dec 10, 1999
Provisional Application 6016961600 · Dec 8, 1999
Provisional Application 6016961700 · Dec 8, 1999
Provisional Application 6016962300 · Dec 8, 1999
Provisional Application 6016862200 · Dec 3, 1999
Provisional Application 6016865400 · Dec 3, 1999
Provisional Application 6016866100 · Dec 3, 1999
Provisional Application 6016866300 · Dec 3, 1999
Provisional Application 6016866400 · Dec 3, 1999
Provisional Application 6016866500 · Dec 3, 1999
Provisional Application 6016866600 · Dec 3, 1999
Provisional Application 6016866700 · Dec 3, 1999
Provisional Application 6016698900 · Nov 23, 1999
Provisional Application 6016706100 · Nov 23, 1999
Provisional Application 6015580400 · Sep 27, 1999
Provisional Application 6015580500 · Sep 27, 1999
Provisional Application 6015580600 · Sep 27, 1999
Provisional Application 6015580700 · Sep 27, 1999
Provisional Application 6015580800 · Sep 27, 1999
Provisional Application 6015437300 · Sep 17, 1999
Provisional Application 6013857200 · Jun 11, 1999
Provisional Application 6013857300 · Jun 11, 1999
Provisional Application 6013857400 · Jun 11, 1999
Provisional Application 6013859700 · Jun 11, 1999
Provisional Application 6013859800 · Jun 11, 1999
Provisional Application 6013859900 · Jun 11, 1999
Provisional Application 6013862500 · Jun 11, 1999
Provisional Application 6013862600 · Jun 11, 1999
Provisional Application 6013862700 · Jun 11, 1999
Provisional Application 6013862800 · Jun 11, 1999
Provisional Application 6013862900 · Jun 11, 1999
Provisional Application 6013863000 · Jun 11, 1999
Provisional Application 6013863100 · Jun 11, 1999
Provisional Application 6013863200 · Jun 11, 1999
Provisional Application 6013863300 · Jun 11, 1999
Provisional Application 6012869400 · Apr 9, 1999
Provisional Application 6012869500 · Apr 9, 1999
Provisional Application 6012869600 · Apr 9, 1999
Provisional Application 6012869700 · Apr 9, 1999
Provisional Application 6012869800 · Apr 9, 1999
Provisional Application 6012869900 · Apr 9, 1999
Provisional Application 6012870000 · Apr 9, 1999
Provisional Application 6012870100 · Apr 9, 1999
Provisional Application 6012870200 · Apr 9, 1999
Provisional Application 6012870300 · Apr 9, 1999
Provisional Application 6012650100 · Mar 26, 1999
Provisional Application 6012650200 · Mar 26, 1999
Provisional Application 6012650300 · Mar 26, 1999
Provisional Application 6012650500 · Mar 26, 1999
Provisional Application 6012650600 · Mar 26, 1999
Provisional Application 6012650700 · Mar 26, 1999
Provisional Application 6012650800 · Mar 26, 1999
Provisional Application 6012651000 · Mar 26, 1999
Provisional Application 6012651100 · Mar 26, 1999
Provisional Application 6012659400 · Mar 26, 1999
Provisional Application 6012659500 · Mar 26, 1999
Provisional Application 6012659600 · Mar 26, 1999
Provisional Application 6012659700 · Mar 26, 1999
Provisional Application 6012659800 · Mar 26, 1999
Provisional Application 6012660000 · Mar 26, 1999
Provisional Application 6012660100 · Mar 26, 1999
Provisional Application 6012660200 · Mar 26, 1999
Provisional Application 6012605100 · Mar 23, 1999
Provisional Application 6012605400 · Mar 23, 1999
Provisional Application 6012581200 · Mar 23, 1999
Provisional Application 6012581500 · Mar 23, 1999
Provisional Application 6012535800 · Mar 19, 1999
Provisional Application 6012535900 · Mar 19, 1999
Provisional Application 6012536100 · Mar 19, 1999
Provisional Application 6012536200 · Mar 19, 1999
Provisional Application 6012536300 · Mar 19, 1999
Provisional Application 6012536400 · Mar 19, 1999
Provisional Application 6012409300 · Mar 12, 1999
Provisional Application 6012409500 · Mar 12, 1999
Provisional Application 6012409600 · Mar 12, 1999
Provisional Application 6012409900 · Mar 12, 1999
Provisional Application 6012414200 · Mar 12, 1999
Provisional Application 6012414300 · Mar 12, 1999
Provisional Application 6012414400 · Mar 12, 1999
Provisional Application 6012414500 · Mar 12, 1999
Provisional Application 6012414600 · Mar 12, 1999
Related Publication 20070032413A1 · Feb 8, 2007