IP Library › Granted Patent US 7,504,484
Granted Patent B2
US 7,504,484 · App. 11/537,235 · Granted Mar 17, 2009

Antibodies to the PRO1561 polypeptide

Assignee: Genentech, Inc.
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Quick Facts
Patent No.
US 7,504,484
App. No.
11/537,235
Granted
Mar 17, 2009
Kind
B2
Abstract

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Claims (5)

1. An isolated antibody that binds to (a) the polypeptide of SEQ ID NO:534, or (b) the polypeptide of SEQ ID NO:534 lacking its associated signal peptide, wherein the antibody is an antagonist of phospholipase activity of the polypeptide.

2. The antibody of claim 1 , wherein the antibody is a monoclonal antibody.

3. The antibody of claim 1 , wherein the antibody is a humanized antibody.

4. The antibody of claim 1 , wherein the antibody is a human antibody.

5. The antibody of claim 1 , wherein the antibody is an antibody fragment.

Continuity (8)
Continuation 1014751300 · May 17, 2002
Continuation 1002807200 · Dec 19, 2001
Continuation PCTUS003267800 · Dec 1, 2000
Continuation In Part PCTUS000434200 · Feb 18, 2000
Continuation In Part PCTUS992831300 · Nov 30, 1999
Continuation In Part 0940329700
Provisional Application 6010332800 · Oct 7, 1998
Related Publication 20070224185A1 · Sep 27, 2007