IP Library Granted Patent US 7,659,718
Granted Patent B1
US 7,659,718 · App. 12/183,391 · Granted Feb 9, 2010

Blip design for random sampling compressed sensing of flyback 3D-MRSI

Assignee: The Board of Trustees of the Leland Stanford Junior University
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Quick Facts
Patent No.
US 7,659,718
App. No.
12/183,391
Granted
Feb 9, 2010
Kind
B1
Abstract

A method of providing a magnetic resonance spectral image (MRSI) is provided. A magnetic resonance imaging excitation is applied. Data is acquired, comprising applying an oscillating gradient in a first dimension and applying blips in at least a second dimension in a pseudo-random order to acquire pseudo-random temporally undersampled spectral data in at least two planes. The pseudo-random order is used to reconstruct a magnetic resonance spectral image in at least two dimensions.

Claims (33)

1. A method of providing a magnetic resonance spectral image (MRSI), comprising:

a) applying a magnetic resonance imaging excitation;

b) acquiring data, comprising:

applying an oscillating gradient in a first dimension, and

applying blips in at least a second dimension in a pseudo-random order to acquire pseudo-random temporally undersampled spectral data in at least two planes; and

c) using the pseudo-random order to reconstruct a magnetic resonance spectral image in at least two dimensions.

2. The method, as recited in claim 1 , wherein the magnetic resonance spectral image is in three dimensions.

3. The method, as recited in claim 2 , wherein the acquiring data uses flyback readouts.

4. The method, as recited in claim 3 , wherein the applying pseudo-random blips applies blips in a third dimension to acquire temporally undersampled spectral data in at least four planes.

5. The method, as recited in claim 4 , wherein the magnetic resonance spectral image in at least two dimensions is a hyperpolarized image.

6. The method of claim 5 , wherein the magnetic resonance spectral image in at least two dimensions is a 13 C 3D hyperpolarized image.

7. The method, as recited in claim 6 , wherein sampling time is reduced by a factor of at least 2.

8. The method, as recited in claim 7 , wherein the acquiring data uses a spin-echo sequence.

9. The method of claim 1 where the reconstruction uses the equation Minimize ∥W g∥ 1 s.t. ∥F k g−y∥ 2 <ε.

10. The method, as recited in claim 1 , wherein the acquiring data uses flyback readouts.

11. The method, as recited in claim 1 , wherein the applying pseudo-random blips applies blips in a third dimension to acquire temporally undersampled spectral data in at least four planes.

12. The method, as recited in claim 1 , wherein the magnetic resonance spectral image in at least two dimensions is a hyperpolarized image.

13. The method of claim 1 , wherein the magnetic resonance spectral image in at least two dimensions is a 13 C 3D hyperpolarized image.

14. The method, as recited in claim 1 , wherein sampling time is reduced by a factor of at least 2.

15. The method, as recited in claim 1 , wherein the acquiring data uses a spin-echo sequence.

16. The method, as recited in claim 1 , further comprising displaying the reconstructed image.

17. An apparatus for providing a magnetic resonance spectral imaging (MRSI), comprising:

a magnetic resonance imaging excitation and detection system; and

a controller electrically connected to the magnetic resonance imaging excitation and detection system, comprising:

a display;

at least one processor; and

computer readable media, comprising:

computer readable code for applying a magnetic resonance imaging excitation;

computer readable code for acquiring data, comprising:

computer readable code for applying an oscillating gradient in a first dimension, and

computer readable code for applying blips in at least a second dimension in a pseudo-random order to acquire pseudo-random temporally undersampled spectral data in at least two planes;

computer readable code for using the pseudo-random order to reconstruct a magnetic resonance spectral image in at least two dimensions; and

computer readable code for displaying the image on the display.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 10, 2012
From: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 027505/0317 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 1, 2008
From: LUSTIG, MICHAEL; PAULY, JOHN M.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 021331/0478 →