Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
View Patent ↗The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided.
1. An isolated polypeptide which is encoded by a nucleic acid molecule comprising a nucleotide sequence which is at least 95% identical to the entire nucleotide sequence of SEQ ID NO: 331.
2. The isolated polypeptide of claim 1 , further comprising heterologous amino acid sequences.
3. An isolated fusion polypeptide comprising the polypeptide of claim 1 operably linked to a heterologous polypeptide.
4. The isolated polypeptide of claim 1 , wherein the isolated polypeptide is encoded by a nucleic acid molecule comprising a nucleotide sequence which is at least 97% identical to the entire nucleotide sequence of SEQ ID NO: 331.
5. The isolated polypeptide of claim 1 , wherein the isolated polypeptide is encoded by a nucleic acid molecule comprising a nucleotide sequence which is at least 98% identical to the entire nucleotide sequence of SEQ ID NO: 331.
6. The isolated polypeptide of claim 4 , further comprising heterologous amino acid sequences.
7. An isolated fusion polypeptide comprising the polypeptide of claim 4 operably linked to a heterologous polypeptide.
8. The isolated polypeptide of claim 5 , further comprising heterologous amino acid sequences.
9. An isolated fusion polypeptide comprising the polypeptide of claim 5 operably linked to a heterologous polypeptide.
10. An isolated polypeptide comprising an amino acid sequence which is at least 95% identical to the entire amino acid sequence of SEQ ID NO: 332.
11. The isolated polypeptide of claim 10 , wherein the isolated polypeptide comprises an amino acid sequence which is at least 97% identical to the entire amino acid sequence of SEQ ID NO: 332.
12. The isolated polypeptide of claim 10 , wherein the isolated polypeptide comprises an amino acid sequence which is at least 98% identical to the entire amino acid sequence of SEQ ID NO: 332.
13. The isolated polypeptide of claim 10 , further comprising heterologous amino acid sequences.
14. An isolated fusion polypeptide comprising the polypeptide of claim 10 operably linked to a heterologous polypeptide.
15. The isolated polypeptide of claim 11 , further comprising heterologous amino acid sequences.
16. An isolated fusion polypeptide comprising the polypeptide of claim 11 operably linked to a heterologous polypeptide.
17. The isolated polypeptide of claim 12 , further comprising heterologous amino acid sequences.
18. An isolated fusion polypeptide comprising the polypeptide of claim 12 operably linked to a heterologous polypeptide.
19. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 332.
20. The isolated polypeptide of claim 19 , further comprising heterologous amino acid sequences.
21. An isolated fusion polypeptide comprising the polypeptide of claim 19 operably linked to a heterologous polypeptide.
22. An isolated polypeptide which is encoded by a nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO: 331.
23. The isolated polypeptide of claim 22 , further comprising heterologous amino acid sequences.
24. An isolated fusion polypeptide comprising the polypeptide of claim 22 operably linked to a heterologous polypeptide.