IP Library › Granted Patent US 7,858,746
Granted Patent B2
US 7,858,746 · App. 12/057,637 · Granted Dec 28, 2010

Substance that specifically recognizes PD-1

Assignees: ONO Pharmaceutical Co., Ltd.; Tasuku Honjo
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Quick Facts
Patent No.
US 7,858,746
App. No.
12/057,637
Granted
Dec 28, 2010
Kind
B2
Abstract

Compounds that can recognize selectively both PD-1 protein and a membrane protein co-existing with PD-1 on a cell membrane, and can transmit a suppressive signal of PD-1. The compounds are useful for medical treatment and/or prevention of diseases caused by immune abnormality.

Claims (2)

1. An isolated polypeptide consisting of the amino acid sequence of SEQ ID NO: 29.

2. An isolated polypeptide consisting of the amino acid sequence of SEQ ID NO: 31.

Priority Claims (1)
JP P.2001-232303 · Jul 31, 2001 · national
Continuity (2)
Division 1048546600
Related Publication 20090076250A1 · Mar 19, 2009