IP Library Granted Patent US 7,876,937
Granted Patent B2
US 7,876,937 · App. 11/532,246 · Granted Jan 25, 2011

Localization of nodules in a radiographic image

Assignee: Carestream Health, Inc.
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Quick Facts
Patent No.
US 7,876,937
App. No.
11/532,246
Granted
Jan 25, 2011
Kind
B2
Abstract

A method for determining a location of an object in a radiographic image by segmentation of a region in the image comprises the steps of: determining a first image intensity that is characteristic of high image intensities in the region; determining a second image intensity that is characteristic of low image intensities outside of the region; and determining if a pixel is added to or removed from the region based on the similarity of the pixel's intensity to the first and second intensity.

Claims (19)

1. A method of determining a location of an object in a radiographic image by segmentation of a region in the image comprising the steps of:

determining, from memory storing the image, a first image intensity in said region, wherein said first image intensity is a maximum intensity of said region;

determining a second image intensity outside of said region, wherein said second image intensity is a minimum intensity outside of said region;

determining if a pixel is added to or removed from said region based on a similarity of an intensity of said pixel to said first and second intensities; and

using contrast energy, modifying a contour of said region to selectively include the pixel within the region based on the determining if a pixel is added to or removed from said region.

2. The method of claim 1 wherein said object is a nodule.

3. The method of claim 2 object is a pulmonary nodule.

4. The method of claim 2 wherein an application of therapeutic radiation to said nodule is modified based on a characteristic of said region.

5. A method of determining a location of an object in a radiographic image by segmentation of a region in the image comprising the steps of:

determining, from memory storing the image, an aim point in said region, wherein said aim point is located at a point in said region with maximum intensity;

identifying an image pixel outside of said region;

determining a direction from said image pixel to said aim point;

determining an image intensity gradient direction at said image pixel;

determining if said image pixel is added to or removed from said region based on a comparison of said direction from said image pixel to said aim point and said image intensity gradient direction; and

using contrast energy, modifying a contour of said region to selectively include the pixel within the region based on the determining if a pixel is added to or removed from said region.

6. The method of claim 5 wherein said object is a nodule.

7. The method of claim 6 wherein said object is a pulmonary nodule.

8. The method of claim 6 wherein an application of therapeutic radiation to said nodule is modified based on a characteristic of said region.

9. The method of claim 5 wherein said point in said region with maximum intensity is a center of the region.

Assignments (10)
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY (SECOND LIEN) Recorded Oct 14, 2022
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL LLC; QUANTUM MEDICAL IMAGING, L.L.C.; TROPHY DENTAL INC.
Reel/Frame 061683/0601 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY (FIRST LIEN) Recorded Oct 14, 2022
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL LLC; QUANTUM MEDICAL IMAGING, L.L.C.; TROPHY DENTAL INC.
Reel/Frame 061683/0441 →
RELEASE OF SECURITY INTEREST Recorded Oct 14, 2022
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL, LLC; QUANTUM MEDICAL IMAGING, L.L.C.; QUANTUM MEDICAL HOLDINGS, LLC; TROPHY DENTAL INC.
Reel/Frame 061681/0380 →
SECOND LIEN INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jul 1, 2013
From: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL LLC; QUANTUM MEDICAL IMAGING, L.L.C.; TROPHY DENTAL INC.
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Reel/Frame 030724/0154 →
AMENDED AND RESTATED INTELLECTUAL PROPERTY SECURITY AGREEMENT (FIRST LIEN) Recorded Jun 28, 2013
From: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL LLC; QUANTUM MEDICAL IMAGING, L.L.C.; TROPHY DENTAL INC.
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Reel/Frame 030711/0648 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY (SECOND LIEN) Recorded Mar 13, 2012
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.
Reel/Frame 027851/0812 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded May 12, 2011
From: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL, LLC; QUANTUM MEDICAL IMAGING, L.L.C.; QUANTUM MEDICAL HOLDINGS, LLC; TROPHY DENTAL INC.
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Reel/Frame 026269/0411 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 7, 2008
From: EASTMAN KODAK COMPANY
To: CARESTREAM HEALTH, INC.
Reel/Frame 020741/0126 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 7, 2008
From: EASTMAN KODAK COMPANY
To: CARESTREAM HEALTH, INC.
Reel/Frame 020756/0500 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2006
From: SCHILDKRAUT, JAY S.; CHEN, SHOUPU
To: EASTMAN KODAK COMPANY
Reel/Frame 018261/0793 →
Continuity (1)
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