Vascular prothesis having interdigitating edges and methods of use
The present invention is directed to an implantable vascular prosthesis configured for use in a wide range of applications, such as treating aneurysms, maintaining patency in a vessel, and providing controlled delivery of therapeutic agents to a vessel wall. The prosthesis comprises a helical body having a plurality of turns, wherein the proximal and distal edges of the turns of the prosthesis has a pattern that interdigitates when the prosthesis assumes the deployed configuration. The prosthesis optionally may comprise a radially expanding distal portion coupled to the helical body for facilitating placement of the prosthesis within a body vessel.
1. A vascular prosthesis for implantation in a body vessel, the vascular prosthesis comprising:
a helical section configured to transition between a contracted, wound-down delivery configuration and an unconstrained, unwound deployed configuration, the helical section comprising at least one unconnected turn extending substantially more than 360° along a helical path when in the deployed configuration, each said turn having a distal edge and a proximal edge;
the helical section comprising a flat ribbon of material having a multiplicity of openings formed therethrough, at least some of the multiplicity of openings define ellipsoidal openings;
the distal and proximal edges each defining a series of generally convex crests and generally concave troughs configured so that in the deployed configuration a series of adjacent crests along the distal edge interdigitates with a series of adjacent troughs along an adjacent proximal edge;
said series of adjacent interdigitating crests along said distal edge extending at least half way into said series of adjacent troughs along said proximal edge; and
said series of adjacent interdigitating crests and troughs extending along at least half of the helical section;
whereby the interdigitating crests and troughs improve the coverage and support of the body vessel.
2. The vascular prosthesis of claim 1 wherein, in the deployed configuration, the series of crests and troughs along the proximal edge is spaced apart from the series of crests and troughs along the distal edge.
3. The vascular prosthesis of claim 1 wherein the helical section comprises a shape memory material.
4. The vascular prosthesis of claim 1 wherein at least some of the ellipsoidal openings are circular openings.
5. The vascular prosthesis of claim 1 wherein the openings are defined by a feature disposed in alignment along a helical axis of the prosthesis.
6. The vascular prosthesis of claim 1 wherein the series of crests and troughs has a repetitive pattern and defines a wavelike configuration.
7. The vascular prosthesis of claim 1 wherein the series of crests and troughs has a repetitive pattern and defines a zig-zag configuration.
8. The vascular prosthesis of claim 1 further comprising a therapeutic agent disposed on the helical section.
9. The vascular prosthesis of claim 1 wherein said series of adjacent interdigitating crests and troughs extend along the entire helical section.