IP Library Granted Patent US 7,955,418
Granted Patent B2
US 7,955,418 · App. 12/066,485 · Granted Jun 7, 2011

Systems for removing dimethyl sulfoxide (DMSO) or related compounds or odors associated with same

Assignee: Abela Pharmaceuticals, Inc.
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Quick Facts
Patent No.
US 7,955,418
App. No.
12/066,485
Granted
Jun 7, 2011
Kind
B2
Abstract

Preferred embodiments of the invention relate to systems for removing dimethyl sulfoxide (DMSO) or related compounds, or odors associated with same. The systems include adsorbents, odor adsorbing fabrics, masks, clean air members and clean air supply assemblies.

Claims (65)

1. An adsorbent for adsorbing dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds, comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer; and

wherein said outer layer comprises a porous coating; and

an indicator for indicating the presence of dimethyl sulfoxide (DMSO) or related compounds.

2. The adsorbent of claim 1 , wherein said indicator comprises permanganate.

3. The adsorbent of claim 1 , wherein said indicator is colored, and is adapted to decrease in color or intensity as dimethyl sulfoxide (DMSO) or related compounds are removed.

4. The adsorbent according to claim 1 , wherein said adsorbing core particles are selected from the group consisting of one or more of the following: activated carbon, an inorganic oxide, a compound having ion exchange capacity, an ion exchange resin, and a chemical deodorizer.

5. An adsorbent for adsorbing dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds, comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer,

wherein said outer layer comprises a porous coating, and

wherein said intermediate layer comprises a metal compound and a water-soluble organic material disposed between the core particles and the porous coating.

6. The adsorbent according to claim 1 or claim 5 , wherein said outer layer consists only of a porous coating.

7. The adsorbent according to claim 1 or claim 5 , wherein said outer layer comprises a polymer selected from the group consisting of one or more of the following: a fluororesin, a polyamide resin, a polyimide resin, a polyester resin, a polystyrene resin, a polyolefin resin, a polycarbonate resin, a polysulfone resin, an acrylic resin, a cellulose resin, a vinyl chloride resin, a polyacetal resin, a polyurethane resin and a copolymer or derivative thereof.

8. The adsorbent according to claim 1 or claim 5 , wherein said outer layer comprises a polymer selected from the group consisting of one or more of the following: polytetrafluoroethylene, polyhexafluoropropylene, polydifluoroethylene, polyvinylidene fluoride, polyvinyl fluoride, and a copolymer or derivative thereof.

9. The adsorbent according to claim 1 or claim 5 , wherein said porous coating has a thickness of about 0.01 μm to about 1,000 μm.

10. The adsorbent according to claim 1 or claim 5 ,, wherein said porous coating has an average pore diameter of about 0.01 μm to about 500 μm.

11. The adsorbent according claim 1 or claim 5 , wherein said porous coating has a porosity of about 3% to about 90%.

12. A method for removing dimethyl sulfoxide (DMSO) metabolites, comprising contacting said metabolites with an adsorbent, said absorbent comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer; and

wherein said outer layer comprises a porous coating.

13. The method of claim 12 , wherein said dimethyl sulfoxide (DMSO) metabolites are produced by an individual receiving dimethyl sulfoxide (DMSO) treatment.

14. A method for removing odors associated with dimethyl sulfoxide (DMSO) or related compounds, comprising exposing said odors to an adsorbent, said absorbent comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer; and

wherein said outer layer comprises a porous coating.

15. A clean air member for removal of dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds comprising the adsorbent according to claim 1 or claim 5 .

16. A clean air supply assembly for removal of dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds comprising the adsorbent according to claim 1 or claim 5 .

17. An apparatus for removing dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds from the exhaust outlet of a medical respiratory ventilator, wherein said apparatus comprises:

a gas scavenging device comprising an adsorbent, said adsorbent comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises absorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odor associated with said compounds:

wherein said intermediate layer contacts said inner layer and said outer layer;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer,

wherein said outer layer comprises a porous coating, and

wherein said gas scavenging device is connected to said exhaust outlet.

18. A face mask for reducing exposure of dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds comprising an adsorbent, said adsorbent comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer, wherein said outer layer comprises a porous coating.

19. A face mask for reducing exposure of dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds comprising:

an outer shield layer comprising a synthetic fiber;

a copper layer comprising a fiber and powdered copper;

a carbon layer comprising a fiber and activated carbon;

a chemical layer comprising a fiber and one or more, odor absorbing chemicals; and

a facial layer comprising a synthetic fiber.

20. The face mask according to claim 19 , wherein said face mask comprises an exhale valve.

21. The face mask according to claim 19 , wherein said face mask is a duckbill mask.

22. A method according to claim 12 or claim 14 , wherein said adsorbent further comprises an indicator for indicating the presence of dimethyl sulfoxide (DMSO) or related compounds.

23. The method according to claim 22 , wherein said indicator comprises permanganate.

24. The method according to claim 22 , wherein said indicator is colored, and is adapted to decrease in color or intensity as dimethyl sulfoxide (DMSO) or related compounds are removed.

25. A method according to claim 12 or claim 14 , wherein said adsorbing core particles are selected from the group consisting of one or more of the following: activated carbon, an inorganic oxide, a compound having ion exchange capacity, an ion exchange resin, and a chemical deodorizer.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 24, 2008
From: CLAUSSEN, HARVEY L.; COZEAN, COLETTE
To: ABELA PHARMACEUTICALS, INC.
Reel/Frame 021583/0645 →
Continuity (5)
Provisional Application 60716271 · Sep 12, 2005
Provisional Application 60716336 · Sep 12, 2005
Provisional Application 60716278 · Sep 12, 2005
Provisional Application 60716369 · Sep 12, 2005
Related Publication 20080251081A1 · Oct 16, 2008