IP Library Granted Patent US 8,039,591
Granted Patent B2
US 8,039,591 · App. 12/427,380 · Granted Oct 18, 2011

Flowable collagen material for dural closure

Assignee: Codman & Shurtleff, Inc.
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Quick Facts
Patent No.
US 8,039,591
App. No.
12/427,380
Granted
Oct 18, 2011
Kind
B2
Abstract

Flowable graft materials are provided which comprise collagen powder and a liquid in an amount sufficient to impart a flowable consistency to the material. The graft materials are sufficiently formable and pliable so as to provide both superior contact with and easier access to a surgical site than typical, more rigid grafts such as collagen sheets. These flowable materials may also be in a fluidized, paste-like and/or gel-like state and may be moldable and/or ejectable. The flowable collagen materials reduce and/or eliminate post implantation problems associated with other materials, e.g. synthetic dural sealants (hemostasis products), such as product swelling after application and implantation. The flowable graft materials are particularly useful as a dural graft.

Claims (6)

1. A method for repairing a damaged dura comprising:

applying a flowable dural graft material comprising a mixture of cross-linked collagen and a liquid to a desired site of dural damage, wherein said collagen is cross-linked prior to the addition of said liquid; and conforming the dural graft material to a curvature of the site of dural damage.

2. The method of claim 1 , wherein the collagen is present in an amount of about 6% wt/wt %.

3. The method of claim 1 , wherein the collagen source is a collagen powder having a particle size in the range of about 10 to 1000 microns.

4. The method of claim 1 , wherein the flowable graft material is applied by ejection from a syringe.

5. The method of claim 1 , wherein the flowable graft material is applied manually.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2018
From: DEPUY SYNTHES PRODUCTS, INC.
To: INTEGRA LIFESCIENCES CORPORATION
Reel/Frame 045180/0382 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 1, 2018
From: DEPUY SPINE, LLC
To: HAND INNOVATIONS LLC
Reel/Frame 045074/0943 →
CHANGE OF NAME Recorded Mar 1, 2018
From: HAND INNOVATIONS LLC
To: DEPUY SYNTHES PRODUCTS, LLC
Reel/Frame 045476/0712 →
CHANGE OF NAME Recorded Mar 1, 2018
From: DEPUY SYNTHES PRODUCTS, LLC
To: DEPUY SYNTHES PRODUCTS, INC.
Reel/Frame 045479/0763 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2018
From: CODMAN & SHURTLEFF, INC.
To: DEPUY SPINE, LLC
Reel/Frame 045058/0627 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 10, 2009
From: SOMMERICH, ROBERT E
To: CODMAN & SHURTLEFF, INC.
Reel/Frame 022938/0936 →
Continuity (2)
Provisional Application 61047149 · Apr 23, 2008
Related Publication 20090269413A1 · Oct 29, 2009