IP Library Granted Patent US 8,050,474
Granted Patent B2
US 8,050,474 · App. 12/408,944 · Granted Nov 1, 2011

System for generation of a composite medical image of vessel structure

Assignee: Siemens Medical Solutions USA, Inc.
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Quick Facts
Patent No.
US 8,050,474
App. No.
12/408,944
Granted
Nov 1, 2011
Kind
B2
Abstract

A system reduces artifacts introduced by patient or table motion during generation of a composite image visualizing contrast agent flow. A system for generation of a composite medical image of vessel structure, includes an imaging device for acquiring multiple sequential images of vessel structure of a portion of patient anatomy in the presence of a contrast agent. An imaging processor aligns individual images of the multiple sequential images with a single particular mask image containing background detail of the portion of patient anatomy in the absence of contrast agent. The imaging processor forms data representing multiple digitally subtracted images by subtracting data representing the single particular mask image from aligned individual images of the multiple sequential images. The imaging processor associates different individual images of the multiple digitally subtracted images with different corresponding visual attributes and combines data representing the digitally subtracted images to form a composite image. A reproduction device presents the composite image to a user.

Claims (144)

1. A system for generation of a composite medical image of vessel structure, comprising:

an imaging device for acquiring a plurality of sequential images of vessel structure of a portion of patient anatomy in the presence of a contrast agent;

an imaging processor for,

aligning individual images of said plurality of sequential images with a single particular mask image containing background detail of said portion of patient anatomy in the absence of contrast agent,

forming data representing a plurality of digitally subtracted images by subtracting data representing said single particular mask image from aligned individual images of said plurality of sequential images,

associating different individual images of said plurality of digitally subtracted images with different corresponding visual attributes and

combining data representing said digitally subtracted images to form a composite image; and

a reproduction device for presenting said composite image to a user.

2. A system according to claim 1 , wherein

said visual attributes are different colors and

said composite image indicates a color representation of blood flow through said vessel structure.

3. A system according to claim 1 , wherein

said visual attributes are different hues and

said composite image indicates a color representation of blood flow through said vessel structure.

4. A system according to claim 1 , wherein

said visual attributes are different shades and

said composite image indicates a shaded representation of blood flow through said vessel structure.

5. A system according to claim 1 , wherein

said imaging processor associates different individual images of said plurality of digitally subtracted images with different corresponding visual attributes in response to relative time of acquisition of said different individual images.

6. A system according to claim 1 , wherein

said plurality of sequential images are associated with a time window of imaging acquisition determined in response to predetermined information.

7. A system according to claim 1 , wherein

the number of said plurality of sequential images is determined in response to predetermined information.

8. A system according to claim 1 , wherein

said imaging processor aligns said individual images of said plurality of sequential images with said single particular mask image using a translational shift vector.

9. A system according to claim 1 , wherein

said imaging processor combines data representing said digitally subtracted images to form a composite image by using acquisition times relative to start of acquisition of images employed in generating said composite image.

10. A system according to claim 9 , wherein

said imaging processor combines data representing said digitally subtracted images to form a composite image by using peak luminance intensity value of individual pixels to determine luminance intensity of respective individual image pixels of said composite image.

11. A system according to claim 1 , wherein

said imaging processor combines data representing said digitally subtracted images to form a composite image by using peak luminance intensity value of individual pixels to determine luminance intensity of respective individual image pixels of said composite image.

12. A system according to claim 1 , wherein

said imaging processor combines data representing said digitally subtracted images to form a composite image using functions, by determining a hue value

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 where H 0 and H f represent starting and ending hues to be used in the output composite color image, T 0 and T f represent starting and ending timestamps of images of said digitally subtracted images used in generation of said composite image, C min and C max represent the minimum and maximum luminance intensity values in said composite image.

13. A system according to claim 1 , wherein

said imaging processor associates different individual pixels of said different individual images of said plurality of digitally subtracted images with different corresponding visual attributes and combines data representing said individual pixels of said digitally subtracted images to form said composite image.

14. A method for generation of a composite medical image of vessel structure, comprising the activities of:

acquiring a plurality of sequential images of vessel structure of a portion of patient anatomy in the presence of a contrast agent;

aligning individual images of said plurality of sequential images with a single particular mask image containing background detail of said portion of patient anatomy in the absence of contrast agent;

forming data representing a plurality of digitally subtracted images by subtracting data representing said single particular mask image from aligned individual images of said plurality of sequential images;

associating different individual images of said plurality of digitally subtracted images with different corresponding colors;

combining data representing said digitally subtracted images to form a composite image indicating a color representation of blood flow through said vessel structure; and

presenting said composite image to a user.

15. A method according to claim 14 , wherein

said activity of associating different individual images of said plurality of digitally subtracted images with different corresponding colors comprises associating different individual pixels of said different individual images of said plurality of digitally subtracted images with different corresponding colors and

said activity of combining data representing said digitally subtracted images comprises combining data representing individual pixels of said digitally subtracted images to form said composite image.

16. A system for generation of a composite medical image of vessel structure, comprising:

an imaging device for acquiring a plurality of sequential images of vessel structure of a portion of patient anatomy in the presence of a contrast agent;

an imaging processor for,

aligning individual images of said plurality of sequential images with a single particular mask image containing background detail of said portion of patient anatomy in the absence of contrast agent,

forming data representing a plurality of digitally subtracted images by subtracting data representing said single particular mask image from aligned individual images of said plurality of sequential images,

associating different individual pixels of different individual images of said plurality of digitally subtracted images with different corresponding colors and

combining data representing said different individual pixels of different individual images of said plurality of digitally subtracted images to form a composite image indicating a color representation of blood flow through said vessel structure; and

a reproduction device for presenting said composite image to a user.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 11, 2022
From: ICE CAP
To: PIXART IMAGING INC.
Reel/Frame 061639/0342 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 30, 2021
From: ALLIED SECURITY TRUST I
To: ICE CAP, SERIES 106 OF ALLIED SECURITY TRUST I
Reel/Frame 058601/0037 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 23, 2021
From: SIEMENS HEALTHCARE GMBH
To: ALLIED SECURITY TRUST I
Reel/Frame 058960/0371 →
CORRECTIVE ASSIGNMENT TO CORRECT THE EXECUTION DATE OF ASSIGNMENT 3, ASSIGNOR SIEMENS MEDICAL SOLUTIONS USA, INC. TO SIEMENS HEALTHCARE GMBH PREVIOUSLY RECORDED ON REEL 043379 FRAME 0673. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT OF INVENTOR RIGHTS.. Recorded Dec 2, 2020
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 056112/0540 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2017
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 043379/0673 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 27, 2009
From: BAUMGART, JOHN
To: SIEMENS MEDICAL SOLUTIONS USA, INC.
Reel/Frame 022739/0045 →
Continuity (2)
Provisional Application 61044114 · Apr 11, 2008
Related Publication 20090257631A1 · Oct 15, 2009