IP Library Granted Patent US 8,068,222
Granted Patent B2
US 8,068,222 · App. 11/757,146 · Granted Nov 29, 2011

Method and apparatus for microlens array/fiber optic imaging

Assignee: ChemImage Corporation
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Quick Facts
Patent No.
US 8,068,222
App. No.
11/757,146
Granted
Nov 29, 2011
Kind
B2
Abstract

A novel approach for chemical imaging is disclosed. In one embodiment, the disclosure relates to a system for producing a spatially accurate wavelength-resolved image of a sample from photons scattered from the sample, comprising an optical lens; a first optical fiber bundle of M fibers; a second optical fiber bundle of N fibers; an optical fiber switch; and a charge coupled device, wherein the image comprises plural sub-images, and wherein each sub-image is formed from photons scattered from a predetermined two spatial dimension portion of the sample, and wherein the scattered photons forming each sub-image have a predetermined wavelength different from a predetermined wavelength of scattered photons forming the other sub-images, and wherein the scattered photons for each sub-image are collected substantially simultaneously.

Claims (28)

1. A system for producing a spatially accurate wavelength-resolved image of a sample from photons

either emitted or reflected from the sample, comprising:

an optical lens collecting the either emitted or reflected photons and delivering imaging photons;

a first optical fiber bundle of M fibers receiving the imaging photons via the optical lens;

a second optical fiber bundle of N fibers receiving the imaging photons via the first optical fiber bundle and

transmitting the imaging photons to a charge coupled device;

an optical fiber switch coupling the first optical fiber bundle and the second optical fiber bundle;

wherein the image comprises plural sub-images, and

wherein each sub-image is formed from photons either emitted or reflected from a predetermined two spatial dimension portion of the sample, and

wherein the either emitted or reflected photons forming each sub-image have a predetermined wavelength different from a predetermined wavelength of either emitted or reflected photons forming the other sub-images, and

wherein the either emitted or reflected photons for each sub-image are collected substantially simultaneously.

2. The system of claim 1 wherein M>N.

3. The system of claim 1 wherein the optical lens provides magnification.

4. The system of claim 1 wherein the spatially accurate wavelength-resolved image is produced without moving the sample.

5. The system of claim 1 wherein the system is polarization-independent.

6. The system of claim 1 wherein the spatially accurate wavelength-resolved image is a Raman image of the sample.

7. The system of claim 1 wherein the optical fiber switch is an electro-optical switch.

8. The system of claim 7 further comprising a controller for controlling the optical fiber switch and the charge coupled device.

9. A method for producing a spatially accurate wavelength-resolved image of a sample from photons either emitted or reflected from the sample, comprising:

collecting photons either emitted or reflected from the sample with an optical lens;

transmitting the collected photons to a first optical fiber bundle;

transmitting the collected photons to a second optical fiber bundle through an optical fiber switch; and

detecting the collected photons with a charge coupled device to thereby produce a spatially accurate wavelength-resolved image of the sample,

wherein the image comprises plural sub-images, and

wherein each sub-image is formed from photons either emitted or reflected from a predetermined two spatial dimension portion of the sample, and

wherein the either emitted or reflected photons forming each sub-image have a predetermined wavelength different from a predetermined wavelength of either emitted or reflected photons forming the other sub-images, and

wherein the either emitted or reflected photons for each sub-image are collected substantially simultaneously.

10. The system of claim 9 wherein the spatially accurate wavelength-resolved image is a Raman image of the sample.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 9, 2013
From: CHEMIMAGE CORPORATION
To: CHEMIMAGE TECHNOLOGIES LLC
Reel/Frame 030573/0454 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 20, 2011
From: ZHANG, JINGYUN
To: CHEMIMAGE CORPORATION
Reel/Frame 027106/0058 →
Continuity (3)
Division 10962662 · Oct 13, 2004
Provisional Application 60583840 · Jun 30, 2004
Related Publication 20100265498A1 · Oct 21, 2010