Portable sample analyzer cartridge
A sample analyzer cartridge for use at a point of care of a patient such as in a doctor's office, in the home, or elsewhere in the field. By providing a removable and/or disposable cartridge with all of the needed reagents and/or fluids, the sample analyzer can be reliably used outside of the laboratory environment, with little or no specialized training.
1. A disposable analysis cartridge capable of performing at least part of a blood sample measurement, comprising:
two or more reagent storage reservoirs, a first one for storing a lysing reagent and a second one for storing a sphering reagent;
a first flow sensor in fluid communication with the first one of the reagent storage reservoirs;
a second flow sensor in fluid communication with the second one of the reagent storage reservoirs;
a lysing on the fly channel in fluid communication with the first one of the reagent storage reservoirs;
a sphering on the fly channel in fluid communication with the second one of the reagent storage reservoirs; and
a first flow cytometry analysis channel structured to hydrodynamically focus a blood sample and to support flow cytometric measurements, the first flow cytometry analysis channel in fluid communication with and downstream of the lysing on the fly channel; and
a second flow cytometry analysis channel structured to hydrodynamically focus a blood sample and to support flow cytometric measurements, the second flow cytometry analysis channel in fluid communication with and downstream of the sphering on the fly channel.