Indole compounds useful as serotonin selective agents
Novel indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
1. A compound of formula (I):
wherein:
R is —CH 3 , —CH 2 CH 3 , —CH 2 CH 2 CH 3 , —CH 2 CH 2 CH 2 CH 3 , -cyclopropylmethyl, —CH(CH 3 ) 2 , —SO 2 CH 3 , or —SO 2 CH 2 CH 3 .
2. A compound of formula (II):
wherein:
R is —CH 3 , —CH 2 CH 3 , —CH 2 CH 2 CH 3 , —CH 2 CH 2 F, —CH 2 CH 2 CH 2 CH 3 , -cyclopropylmethyl, —CH(CH 3 ) 2 , —SO 2 CH 3 , or —SO 2 CH 2 CH 3 .
3. A compound of the following formula:
4. A compound of the following formula:
5. A compound of the following formula:
6. The compound of claim 1 , wherein the compound is:
7. The compound of claim 1 , wherein the compound is:
8. The compound of claim 1 , wherein the compound is:
9. The compound of claim 1 , wherein the compound is:
10. The compound of claim 1 , wherein the compound is:
11. The compound of claim 1 , wherein the compound is:
12. The compound of claim 2 , wherein the compound is:
13. The compound of claim 2 , wherein the compound is:
14. The compound of claim 2 , wherein the compound is:
15. The compound of claim 2 , wherein the compound is:
16. The compound of claim 2 , wherein the compound is:
17. The compound of claim 2 , wherein the compound is:
18. The compound of claim 2 , wherein the compound is:
19. The compound of claim 2 , wherein the compound is: