Blood flow restorative and embolus removal methods

1. A method for restoring blood flow in an occluded cerebral blood vessel of a patient during acute ischemic stroke, comprising:

accessing an cerebral blood vessel having an occluded zone with a catheter system, the catheter system comprising a microcatheter and an embolus removal device;

wherein the embolus removal device comprises a self-expandable member configured to be delivered through the microcatheter in a compressed configuration and deployed to an expanded configuration upon retraction of the microcatheter,

wherein the self-expandable member comprises a generally cylindrical body having a cell structure configured to facilitate embolus attachment to the self-expandable member;

locating the occluded zone within the artery caused by an embolus;

advancing the catheter system to the location of the occluded zone;

deploying the self-expandable member to the expanded configuration at the location of the occluded zone by retracting the microcatheter such that the self-expandable member engages and captures the embolus upon deployment of the self-expandable member,

wherein the embolus is at least partially engaged and captured on an external surface of the self-expandable member; and

removing the embolus by withdrawing the embolus removal device.

2. The method of claim 1 , wherein a first end of the self-expandable member operatively abuts the embolus.

3. The method of claim 1 , wherein engaging the embolus facilitates autolysis of the embolus or any fragments of the embolus remaining in the artery.

4. The method of claim 1 , the removing step further comprising moving the engaged embolus down the intracranial tree to a more stable location.

5. The method of claim 1 , wherein the cell structure of the body of the self-expandable member comprises variable cell size at different portions of the body.

6. The method of claim 1 , wherein a distal end of the self-expandable member of the embolus removal device is open in the expanded configuration.

7. The method of claim 1 , wherein said self-expandable member is permanently coupled to a distal end of a delivery member by a plurality of tether lines.

8. The method of claim 1 , wherein the embolus resides at least partially within the capture device upon being captured.

9. The method of claim 5 , wherein the cell size of the body of the capturing device is larger in the middle section of the body.

10. A method for restoring blood flow in an occluded cerebral blood vessel of a patient, comprising:

accessing a cerebral artery having an occluded zone with a catheter system, the catheter system comprising a microcatheter and a blood flow restoration device,

wherein the blood flow restoration device comprises a distal self-expandable capture device and a proximal delivery member,

wherein the distal self-expandable capture device is eccentrically coupled to the proximal delivery member by a plurality of tether lines,

wherein the distal self-expandable capture device is configured to be delivered through the microcatheter in a compressed configuration and deployed to an expanded configuration upon retraction of the microcatheter;

locating the occluded zone within the artery caused by an occlusive object;

advancing the catheter system to the location of the occluded zone;

deploying the distal self-expandable capture device to the expanded configuration at the location of the occluded zone by retracting the microcatheter such that the capture device engages and captures the occlusive object upon deployment of the capture device,

wherein the occlusive object is at least partially engaged and captured on an external surface of the capture device; and

removing the occlusive object by withdrawing the blood flow restoration device.

11. The method of claim 10 , wherein the occluding object comprises any one of the following non-limiting examples: an embolus, a thrombus, a blood clot, a calcified lesion, or any other obstruction within a blood vessel.

12. The method of claim 10 , wherein the occlusive object resides at least partially within the capture device upon being captured.