Cell delivery catheter and method
View Patent ↗A cell delivery catheter having one of more apearutres is used to positon and deliver cells to an implant site in a patient.
1. A cell delivery catheter system for delivering and positioning cells in a patient's body, comprising:
a catheter body having a proximal end and a distal end, said catheter body defining a central axis;
a plurality of optical fibers embedded within the catheter body or placed upon its outer or inner surface for conveying illumination to and optical signals from the target tissues;
a cell delivery barrel located within said catheter body having a distal aperture;
lumens surrounding the cell delivery barrel for delivery of said cells;
the cell delivery barrel having a volume to carry and deliver cells within said volume;
a source of fluid coupled to said cell delivery barrel for ejecting said cells from said cell delivery barrel under the control of the user; and
wherein said optical fibers in said catheter body provide a cytometry means to count cells that pass though port holes of said catheter.
2. The catheter system of claim 1 , wherein some of said optical fibers deliver light to and some of said optical fibers gather light from port holes on said catheter body.
3. The catheter system of claim 1 , wherein said optical fibers are collectively used to optically monitor the passage of individual cells through port holes via fluorescence of the cells.
4. The catheter system of claim 3 , wherein fluorescence-based signals associated with cell passage through port holes provide a feedback control means to regulate a pump or other actuator driving the flow of said cells.
5. The catheter system of claim 1 wherein at least one optical fiber emits radiation and another optical fiber collects and transmits collected radiation.
6. The catheter system of claim 1 wherein the emitted radiation is ultraviolet radiation and collected radiation is fluorescing radiation.
7. The catheter system of claim 1 wherein at least some optical fibers receive and transmit light as part of cell counting device.
8. A cell delivery catheter system for delivering and positioning cells in a patient's body, comprising:
a catheter body having a proximal end and a distal end, said catheter body defining a central axis;
a plurality of optical fibers embedded within the catheter body or placed upon its outer or inner surface for conveying illumination to and optical signals from the target tissues;
a cell delivery barrel located within said catheter body having a distal aperture;
a plurality of lumens adjacent the cell delivery barrel for delivery of said cells;
the cell delivery barrel having a volume to carry and deliver cells within said volume;
a source of fluid coupled to said cell delivery barrel for ejecting said cells from said cell delivery barrel under the control of the user; and
wherein said optical fibers in said catheter body provide a cytometry means to count cells that pass though port holes of said catheter.
9. The catheter system of claim 8 , wherein some of said optical fibers deliver light to and some of said optical fibers gather light from port holes on said catheter body.
10. The catheter system of claim 8 , wherein said optical fibers are collectively used to optically monitor the passage of individual cells through port holes via fluorescence of the cells.
11. The catheter system of claim 8 , wherein fluorescence-based signals associated with cell passage through said port holes provide a feedback control means to regulate a pump or other actuator driving the flow of said cells.
12. The catheter system of claim 8 wherein at least one optical fiber emits radiation and another optical fiber collects and transmits collected radiation.
13. The catheter system of claim 8 wherein the emitted radiation is ultraviolet radiation and collected radiation is fluorescing radiation.
14. The catheter system of claim 8 wherein at least some optical fibers receive and transmit light as part of cell counting device.