IP Library › Granted Patent US 8,124,742
Granted Patent B2
US 8,124,742 · App. 11/064,174 · Granted Feb 28, 2012

Rh(D)-binding proteins

Assignee: The Trustees of the University of Pennsylvania
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Quick Facts
Patent No.
US 8,124,742
App. No.
11/064,174
Granted
Feb 28, 2012
Kind
B2
Abstract

The invention includes Rh(D) binding proteins, including antibodies, and DNA encoding such proteins. Methods of generating such proteins and DNAs are also included.

Claims (3)

1. An isolated antigen-binding protein comprising a heavy chain and light chain, wherein the amino acid sequence of the heavy chain is a sequence selected from the group consisting of SEQ ID NOs: 1-28 and 139-153 and the amino acid sequence of the light chain is a sequence selected from the group consisting of SEQ ID NOs: 29-69 and 154-181, further wherein said protein is an antibody that binds to Rh(D).

2. The isolated antigen-binding protein of claim 1 , wherein said protein is an antibody fusion protein.

3. The isolated antigen-binding protein of claim 1 , wherein said protein is substantially purified.

Continuity (8)
Division 09240274 · Jan 29, 1999
Continuation In Part 08884045 · Jun 27, 1997
Continuation In Part 11064174
Continuation 09848798 · May 4, 2001
Division 09240274
Provisional Application 60081380 · Apr 10, 1998
Provisional Application 60028550 · Oct 11, 1996
Related Publication 20050282252A1 · Dec 22, 2005