IP Library Granted Patent US 8,137,256
Granted Patent B2
US 8,137,256 · App. 11/305,437 · Granted Mar 20, 2012

Brachytherapy apparatus

Assignee: Portola Medical, Inc.
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Quick Facts
Patent No.
US 8,137,256
App. No.
11/305,437
Granted
Mar 20, 2012
Kind
B2
Abstract

The present disclosure provides a brachytherapy apparatus that delivers a low dose, partial breast irradiation treatment for post-lumpectomy patients via introduction of a catheter-like device through a cannula. The apparatus may be introduced post-surgically with local anesthesia under image guidance into the previous excision site and into a cavity by a surgeon. The brachytherapy apparatus includes a seed containment device configured to contain a plurality of low-dose radioactive seeds therein. The seed containment device may be one or more thin-walled tubes. The apparatus is further configured to expand so that at least a portion of the seed containment device is positioned against the remaining tissue and the plurality of radioactive seeds are disposed at the perimeter of the seed containment device. Also described are various clamps for the apparatus, and sleeves for adjusting the size of the device to fit a cavity when the apparatus is in use.

Claims (18)

1. A method for delivering localized irradiation to tissue near a cavity that lies beneath a surface of a body with a brachytherapy apparatus that includes a plurality of tubes configured to controllably move from a collapsed state to an expanded state while within the cavity, the method comprising in the order recited:

inserting the tubes while in the collapsed state into the cavity such that a first portion of the tubes lies within the cavity and a second portion of the tubes lies outside of the body;

expanding the first portion of the tubes from the collapsed state to the expanded state while the first portion of the tubes remains within the cavity;

cutting the tubes at a location on the tubes that is just outside of the body, thereby removing the portion of the tubes from the brachytherapy apparatus; and

inserting one or more radioactive seeds into one or more of the tubes.

2. The method of claim 1 wherein the body is a breast and the cavity is within the breast.

3. The method of claim 2 wherein the brachytherapy apparatus includes a member that is configured to be sutured to the surface of the breast, the method further comprising suturing the member to the surface of the breast.

4. The method of claim 1 further comprising clamping the tubes while in the expanded state to prevent the tubes from returning to the collapsed state.

5. The method of claim 1 further comprising covering the cut end of the tubes.

6. The method of claim 5 wherein the covering the cut end of the tubes includes placing a removable cap over the cut end of the tubes.

7. A method for delivering localized irradiation to tissue near a cavity that lies beneath a surface of the body with a brachytherapy apparatus that includes a plurality of tubes configured to controllably move from a collapsed state to an expanded state while within the cavity, the method comprising:

while the tubes are in the collapsed state, sliding a sleeve surrounding a first length of the tubes to adjust the length of a second length of the tubes that is not surrounded by the sleeve so as to cause the second length of the tubes, when later expand, to be substantially the size of the cavity, the second length of tubes remaining collapse during the sliding of the sleeve;

inserting the tubes while in the collapsed state into the cavity such that the second length of the tubes lies substantially within the cavity;

expanding the second length of the tubes while within the cavity without also expanding the first length of tubes and without sliding the sleeve; and

inserting one or more radioactive seeds into one or more of the tubes.

8. The method of claim 7 wherein the body is a breast and the cavity is within the breast.

9. The method of claim 7 further comprising clamping the tubes while in the expanded state to prevent the tubes from returning to the collapsed state.

10. The method of claim 7 further comprising cutting the tubes after the tubes are positioned within the cavity and expanded at a location on the tubes that is near flush with and just outside of the body, thereby removing a portion of the tubes from the brachytherapy apparatus.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Apr 1, 2010
From: AGILITY CAPITAL, LLC
To: NORTH AMERICAN SCIENTIFIC, INC.
Reel/Frame 024170/0405 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE, PRE Recorded Sep 25, 2009
From: NORTH AMERICAN SCIENTIFIC, INC.
To: PORTOLA MEDICAL, INC.
Reel/Frame 023330/0313 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 16, 2009
From: NORTH AMERICAN SCIENTIFIC, INC.
To: PORTOLA MEDICAL, INC.
Reel/Frame 023234/0726 →
SECURITY AGREEMENT Recorded Sep 24, 2007
From: NORTH AMERICAN SCIENTIFIC, INC. (DELAWARE CORPORATION); NORTH AMERICAN SCIENTIFIC, INC. (CALIFORNIA CORPORATION)
To: AGILITY CAPITAL, LLC
Reel/Frame 019864/0357 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 25, 2006
From: CUTRER, L. MICHAEL; TERWILLIGER, RICHARD A; WINCH, FREDRICK; ZHANG, JOHN; HIGGINS, WAYNE; BOSSI, DAVID; ELLARD, TERENCE
To: NORTH AMERICAN SCIENTIFIC, INC.
Reel/Frame 017678/0320 →
Continuity (1)
Related Publication 20070142694A1 · Jun 21, 2007