Methods for inhibiting sensory responses in the skin such as pain and itch using topical product formulations containing strontium
Methods for inhibiting sensory responses in the skin such as pain and itch using topical formulations containing aqueous-soluble divalent strontium cation in a suitable topical keratinized skin formulation vehicle are disclosed.
1. A method for reducing irritation comprising the steps of:
preparing a composition comprising:
an aqueous-soluble strontium cation;
a skin penetration enhancer; and
a delivery vehicle; and
topically administering the composition to keratinized skin.
2. The method according to claim 1 , wherein the composition further comprises a counterion.
3. The method according to claim 2 , wherein the counterion further comprises an inorganic anion.
4. The method according to claim 3 , wherein the inorganic anion further comprises a halogen selected from the group consisting of: F, Cl, Br, and I.
5. The method according to claim 3 , wherein the inorganic anion further comprises a nitrate.
6. The method according to claim 4 , wherein the halogen is Cl.
7. The method according to claim 1 , wherein the delivery vehicle is water.
8. The method according to claim 1 , wherein the composition further comprises an organic solvent.
9. The method according to claim 8 , wherein the organic solvent is a glycol.
10. The method according to claim 6 , wherein the delivery vehicle is water.
11. The method according to claim 1 , wherein the irritation results in stinging, burning, itching, redness, swelling or inflammation.