Medical devices including metallic films
Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film and one or more polymer layers. The polymer layers contribute to mechanical or biological properties of the endoprosthesis.
1. An endoprosthesis, comprising:
a generally tubular metallic film having a plurality of plates; and
a framework, at least a portion of which is covered by the generally tubular metallic film;
wherein at least 10% of the plurality of plates are overlapped in a radially compressed state.
2. The endoprosthesis of claim 1 , wherein at least 25% of the plurality of plates are overlapped in a radially compressed state.
3. The endoprosthesis of claim 1 , wherein at least 50% of the plurality of plates are overlapped in a radially compressed state.
4. The endoprosthesis of claim 1 , wherein 30% or less of the plurality of plates are overlapped in a radially expanded state.
5. The endoprosthesis of claim 1 , wherein 10% or less of the plurality of plates are overlapped in a radially expanded state.
6. The endoprosthesis of claim 1 , wherein a tip of a plate overlaps with a base of an adjacent plate in the radially compressed state.
7. The endoprosthesis of claim 1 , wherein the generally tubular metallic film has a surface area in a radially expanded state greater than a surface area in the radially compressed state.
8. The endoprosthesis of claim 1 , wherein the plurality of plates are connected by a plurality of struts.
9. The endoprosthesis of claim 8 , wherein each strut defines a bend of at least 130°.
10. The endoprosthesis of claim 1 , wherein two adjacent plates in the generally tubular metallic film are separated by a gap in a radially expanded state.
11. The endoprosthesis of claim 1 , wherein the generally tubular metallic film has a thickness of less than about 50 μm.
12. The endoprosthesis of claim 1 , wherein the generally tubular metallic film comprises nickel, titanium, and optionally chromium.
13. The endoprosthesis of claim 12 , wherein the generally tubular metallic film comprises nickel, titanium, and chromium, the plurality of plates are connected by a plurality of struts, the plurality of plates have an amount of chromium different than that of the plurality of struts.
14. An endoprosthesis, comprising:
a generally tubular metallic film having a plurality of plates;
wherein at least 10% of the plurality of plates are overlapped in a radially compressed state and a tip of a plate overlaps with a base of an adjacent plate in the radially compressed state.
15. The endoprosthesis of claim 14 , further comprising a framework, at least a portion of which is covered by the generally tubular metallic film.
16. An endoprosthesis, comprising:
a generally tubular metallic film having a plurality of plates connected by a plurality of struts, each strut defining a bend of at least 130°;
wherein at least 10% of the plurality of plates are overlapped in a radially compressed state.
17. The endoprosthesis of claim 16 , further comprising a framework, at least a portion of which is covered by the generally tubular metallic film.
18. An endoprosthesis, comprising:
a generally tubular metallic film having a plurality of plates;
wherein at least 10% of the plurality of plates are overlapped in a radially compressed state and two adjacent plates in the generally tubular metallic film are separated by a gap in a radially expanded state.
19. The endoprosthesis of claim 18 , further comprising a framework, at least a portion of which is covered by the generally tubular metallic film.
20. An endoprosthesis, comprising:
a generally tubular metallic film having a plurality of plates;
wherein at least 10% of the plurality of plates are overlapped in a radially compressed state, the generally tubular metallic film comprises nickel, titanium, and chromium, the plurality of plates are connected by a plurality of struts, the plurality of plates have an amount of chromium different than that of the plurality of struts.
21. The endoprosthesis of claim 20 , further comprising a framework, at least a portion of which is covered by the generally tubular metallic film.