IP Library Granted Patent US 8,207,109
Granted Patent B2
US 8,207,109 · App. 10/250,361 · Granted Jun 26, 2012

Food supplement with a slimming effect

Assignee: Sigma-Tau Industrie Farmaceutiche Riunite SpA
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Quick Facts
Patent No.
US 8,207,109
App. No.
10/250,361
Granted
Jun 26, 2012
Kind
B2
Abstract

A food supplement with a “slimming” effect is disclosed which strengthens the skeletal muscle, protecting the cardio-vascular apparatus of the user, and has as its characterising components propionyl L-carnitine, coenzyme Q 10 nicotinamide, riboflavin and pantothenic acid.

Claims (124)

1. A method of inducing an overall weight loss in a subject or maintaining a constant weight with a diet enriched in carbohydrates or fats, without contemporarily having an anorexia-inducing effect and without changing the eating habits, in addition, leading to skeletal muscle enhancement in the subject, the method comprising administering to a subject a dietary composition consisting of:

a. propionyl L-carnitine or a pharmacologically acceptable salt thereof;

b. coenzyme Q10;

c. nicotinamide;

d. riboflavin; and

e. pantothenic acid,

wherein the weight ratio (a):(b):(c):(d):(e) ranges from 10:0.04:0.08:0.08:0.4 to 1:4:10:4:20; thereby inducing an overall weight loss or maintaining a constant weight in said subject because of increased oxidative metabolism of muscle cells.

2. The method of claim 1 , wherein the weight ratio (a):(b):(c):(d):(e) ranges from 10:2:5:2:2 to 1:1:4:1:5.

3. A method of inducing an overall weight loss in a subject or maintaining a constant weight with a diet enriched in carbohydrates or fats, without contemporarily having an anorexia-inducing effect and without changing the eating habits, in addition, leading to skeletal muscle enhancement in the subject, the method comprising administering to a subject a dietary composition consisting of:

a. propionyl L-carnitine or a pharmacologically acceptable salt thereof;

b. coenzyme Q10;

c. nicotinamide;

d. riboflavin;

e. pantothenic acid, and at least one member of elements f), g) and h) below

f. a carnitine selected from the group consisting of L-carnitine, acetyl L-carnitine, valeryl L-carnitine, isovaleryl L-carnitine and butyryl L-carnitine or a pharmacologically acceptable salt thereof;

g. an amino acid selected from the group consisting of valine, leucine and isoleucine or mixtures thereof;

h. a creatine selected from the group consisting of creatine and phosphocreatine or mixtures thereof;

wherein the weight ratio (a):(b):(c):(d):(e) ranges from 10:0.04:0.08:0.08:0.4 to 1:4:10:4:20; thereby inducing an overall weight loss or maintaining a constant weight in said subject because of increased oxidative metabolism of muscle cells.

4. The method of claim 3 , wherein the weight ratio (a):(b):(c):(d):(e) ranges from 10:2:5:2:2 to 1:1:4:1:5.

5. The method of claim 1 , wherein the dietary composition is in unit dosage form and consists of:

a.

Propionyl L-carnitine

from

50 mg to 2,000 mg

b.

coenzyme Q10

from

 5 mg to 200 mg

c.

nicotinamide

from

10 mg to 500 mg

d.

riboflavin

from

 5 mg to 200 mg

e.

pantothenic acid

from

10 mg to 1,000 mg.

6. The method of claim 5 , wherein the dietary composition has the following composition:

a.

Propionyl L-carnitine

250

mg

b.

coenzyme Q10

20

mg

c.

nicotinamide

50

mg

d.

riboflavin

20

mg

e.

pantothenic acid

20

mg.

7. A method of inducing an overall weight loss in a subject or maintaining a constant weight with a diet enriched in carbohydrates or fats without contemporarily having an anorexia-inducing effect and without changing the eating habits, in addition, leading to skeletal muscle enhancement in the subject, the method comprising administering to a subject a dietary composition consisting of:

a.

Propionyl L-carnitine

from

50 mg to 2,000 mg

b.

coenzyme Q10

from

 5 mg to 200 mg

c.

nicotinamide

from

10 mg to 500 mg

d.

riboflavin

from

 5 mg to 200 mg

e.

pantothenic acid

from

10 mg to 1,000 mg;

thereby inducing an overall weight loss or maintaining a constant weight in said subject because of increased oxidative metabolism of muscle cells.

8. A method of inducing an overall weight loss in a subject or maintaining a constant weight with a diet enriched in carbohydrates or fats, without contemporarily having an anorexia-inducing effect and without changing the eating habits, in addition, leading to skeletal muscle enhancement, in the subject, the method comprising administering to a subject a dietary composition in unit dosage form consisting of:

a.

Propionyl L-carnitine

250

mg

b.

coenzyme Q10

20

mg

c.

nicotinamide

50

mg

d.

riboflavin

20

mg

e.

pantothenic acid

20

mg;

thereby inducing an overall weight loss or maintaining a constant weight in said subject because of increased oxidative metabolism of muscle cells.

9. A method of inducing an overall weight loss in a subject or maintaining a constant weight with a diet enriched in carbohydrates or fats, without contemporarily having an anorexia-inducing effect and without changing the eating habits, in addition, leading to skeletal muscle enhancement in the subject, the method comprising administering to a subject a dietary composition consisting of:

a. propionyl L-carnitine or a pharmacologically acceptable salt thereof;

b. coenzyme Q10;

c. nicotinamide;

d. riboflavin; and

e. pantothenic acid,

wherein the weight ratio (a):(b):(c):(d):(e) ranges from 10:0.04:0.08:0.08:0.4 to 1:4:10:4:20 and wherein the ingredients are administered admixed together or separately; thereby inducing an overall weight loss or maintaining a constant weight in said subject because of increased oxidative metabolism of muscle cells.

10. The method of claim 9 , wherein the weight ratio (a):(b):(c):(d):(e) ranges from 10:2:5:2:2 to 1:1:4:1:5.

11. A method of inducing an overall weight loss in a subject or maintaining a constant weight with a diet enriched in carbohydrates or fats, without contemporarily having an anorexia-inducing effect and without changing the eating habits, in addition, leading to skeletal muscle enhancement in the subject, the method comprising administering to a subject a dietary composition consisting of:

a. propionyl L-carnitine or a pharmacologically acceptable salt thereof;

b. coenzyme Q10;

c. nicotinamide;

d. riboflavin;

e. pantothenic acid, and

f. a carnitine selected from the group consisting of L-carnitine, acetyl-L-carnitine, valeryl-L-carnitine, isovaleryl-L-carnitine and butyryl-L-carnitine or a pharmacologically acceptable salt thereof or mixtures thereof; and/or;

g. an amino acid selected from the group consisting of valine, leucine and isoleucine or mixtures thereof;

h. a creatine selected from the group consisting of creatine and phosphocreatine or mixtures thereof,

wherein the weight ratio (a):(b):(c):(d):(e) ranges from 10:0.04:0.08:0.08:0.4 to 1:4:10:4:20 and wherein the ingredients are administered admixed together or separately; thereby inducing an overall weight loss or maintaining a constant weight in said subject because of increased oxidative metabolism of muscle cells.

12. The method of claim 11 , wherein the weight ratio (a):(b):(c):(d):(e) ranges from 10:2:5:2:2 to 1:1:4:1:5.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 23, 2009
From: SIGMA-TAU HEALTHSCIENCE S.P.A.
To: SIGMA TAU - INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
Reel/Frame 022295/0918 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 1, 2003
From: GAETANI, FRANCO
To: SIGMA-TAU HEALTHSCIENCE S.P.A.
Reel/Frame 014606/0400 →
Priority Claims (1)
IT RM2001A0044 · Jan 29, 2001 · national
Continuity (1)
Related Publication 20040028668A1 · Feb 12, 2004