IP Library Granted Patent US 8,268,990
Granted Patent B2
US 8,268,990 · App. 12/274,915 · Granted Sep 18, 2012

Compounds

Assignees: AstraZeneca AB; Dainippon Sumitomo Pharma Co., Ltd.
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Quick Facts
Patent No.
US 8,268,990
App. No.
12/274,915
Granted
Sep 18, 2012
Kind
B2
Abstract

The present invention provides compounds of formula (I) wherein R 1 , R 2 , R 3 and R 4 are as defined in the specification, and pharmaceutically acceptable salts thereof, as well as processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

Claims (4)

1. A compound, which is 4-(dimethylamino)butyl 2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)acetate, or a pharmaceutically acceptable salt thereof.

2. A compound, which is 4-(dimethylamino)butyl 2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)acetate.

3. A compound, which is a pharmaceutically acceptable salt of 4-(dimethylamino)butyl 2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)acetate.

4. A pharmaceutical composition comprising a compound as claimed in any one of claims 1 to 3 in association with a pharmaceutically acceptable adjuvant, diluent or carrier.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 8, 2012
From: ASTRAZENECA UK LIMITED
To: ASTRAZENECA AB
Reel/Frame 028340/0235 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 8, 2012
From: ASTRAZENECA AB
To: ASTRAZENECA AB; DAINIPPON SUMITOMO PHARMA CO., LTD
Reel/Frame 028340/0260 →
CONFIRMATION OF ASSIGNMENT Recorded Jun 8, 2012
From: TIDEN, ANNA-KARIN
To: ASTRAZENECA AB
Reel/Frame 028341/0580 →
CONFIRMATION OF ASSIGNMENT Recorded Jun 8, 2012
From: BENNETT, NICHOLAS JAMES; MCINALLY, THOMAS; MOCHEL, TOBIAS; THOM, STEPHEN
To: ASTRAZENECA UK LIMITED
Reel/Frame 028341/0774 →
Priority Claims (1)
SE 0702577 · Nov 22, 2007 · national
Continuity (2)
Provisional Application 61013699 · Dec 14, 2007
Related Publication 20090209524A1 · Aug 20, 2009