IP Library Granted Patent US 8,269,196
Granted Patent B2
US 8,269,196 · App. 12/439,440 · Granted Sep 18, 2012

Heavy ion radiation therapy system with stair-step modulation

Assignee: Wisconsin Alumni Research Foundation
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Quick Facts
Patent No.
US 8,269,196
App. No.
12/439,440
Granted
Sep 18, 2012
Kind
B2
Abstract

A system for modulating a fan beam for radiation treatment employs shutters that may move rapidly into and out of different beamlets of a fan beam, the shutters having a systematic weighting so that a limited number of shutters may obtain a far greater number of regularly spaced energy reductions.

Claims (29)

1. A therapeutic radiation modulator comprising:

an inlet receiving a fan beam of radiation movable over a range of angular positions about a patient, and comprised of adjacent beamlets traveling along axes, the fan beam having a cross-sectional area perpendicular to a propagation of the radiation whose greatest dimension extends along a plane and whose least dimension defines a fan beam thickness;

a set of arrays of modulation elements, the arrays positioned side-by-side along the plane, the modulation elements of each array aligned with a different beamlet, each modulation element movable along the fan beam width between an extended position extending fully through the fan beam width and a retracted position outside of the fan beam;

a set of bistable actuators communicating with each modulation element to independently actuate the modulation elements to move them only to the extended or retracted positions at each discrete angular position during movement of the fan beam over the range of angular positions about the patient;

a control system communicating with each bistable actuator to independently activate the bistable actuators;

wherein different modulation elements provide predetermined effective thicknesses so that a series of regular increments of energy reduction can be provided in different beamlets of the fan beam by selection of different combinations of the modulation elements for actuation; and

wherein the modulation elements of each array provide a sequence of increasing effective thicknesses combinable to provide the regular increments of energy attenuation.

2. The therapeutic radiation modulator of claim 1 wherein the bistable actuators independently actuate the modulation elements to move the modulation elements between only two states, a retracted position outside of the beamlet cross-section and an extended position to fully block the beamlet cross-section.

3. The therapeutic radiation modulator of claim 1 wherein the radiation is selected from the group consisting of photon radiation and ion radiation.

4. The therapeutic radiation modulator of claim 1 wherein the sequence of increasing effective thicknesses is a binary power series.

5. The therapeutic radiation modulator of claim 1 wherein the modulation elements have equal thicknesses.

6. The therapeutic radiation modulator of claim 1 further including two sets of modulation elements positioned in opposition across the plane.

7. The therapeutic radiation modulator of claim 1 wherein the modulation elements of an array are of uniform material and have different thicknesses along the axes within the beamlet cross-sectional area of one beamlet when in the extended position, providing different reductions in radiation.

8. The therapeutic radiation modulator of claim 1 wherein the modulation elements of different thicknesses are ordered within the beam to create jumps in thicknesses between successive modulation elements deviating from an ordering according to thickness.

9. The therapeutic radiation modulator of claim 1 further wherein the modulation elements of an array have different densities providing different reductions in radiation.

10. The therapeutic radiation modulator of claim 1 wherein the modulation elements of an array may in combination completely block the radiation to provide for intensity modulation of the radiation through duty-cycle modulation of the bistable actuators.

11. The method of claim 1 wherein a distance between the extended position and the retracted position is equal to a length of the beam cross-sectional area covered by the modulation element when in the extended position.

12. A method of modulating an ion beam comprising:

(a) receiving a fan beam of ions rotating over a range of angular positions about a patient, and traveling along an axis, the fan beam having a cross-sectional area perpendicular to a propagation of the ions whose greatest dimension extends along a plane and whose least dimension defines a fan beam thickness, the fan beam providing a plurality of beamlets positioned side by side in the plane;

(b) positioning a set of arrays of modulation elements so that the modulation elements of each array are spaced along the axis, wherein each modulation element is movable substantially perpendicularly to the plane between an extended position within a beamlet cross-sectional area of one corresponding beamlet and a retracted position outside of the beamlet cross-sectional area of one corresponding beamlet, and so that the arrays of modulation elements are positioned adjacent to each other perpendicular to the axis wherein the modulation elements for each array together provide a sequence of increasing effective thicknesses combinable to provide regular increments of energy attenuation, wherein the area of the fan beam obstructed by each modulation element in the extended position defines a corresponding beamlet; and

(c) controlling a set of bistable actuators communicating with each modulation element to independently control the modulation elements to move them only to the retracted position or the extended position at each discrete angular position during movement of the fan beam over the range of angular positions about the patient so that the series of regular increments of effective thickness of modulation elements within the beam can be provided by selection of different combinations of the modulation elements for actuation; and

(d) activating a control system communicating with each bistable actuator to independently activate the bistable actuators.

13. The method of claim 12 wherein the sequence of increasing effective thicknesses is a binary power series.

14. The method of claim 12 further wherein the thicknesses of the modulation elements are equal.

15. The method of claim 12 further including two sets of modulation elements positioned in opposition across a greatest dimension of the cross-sectional area of the fan beam.

16. The method of claim 12 wherein the modulation elements of an array are of uniform material and have different thicknesses within the beamlet cross-sectional area when in the extended position providing different reductions in ion beam energy.

17. The method of claim 12 wherein the modulation elements of an array have different densities providing different reductions in ion beam energy.

18. The method of claim 12 further wherein the bistable actuators of an array may in combination, stop transmission of the ion beam and the bistable actuators duty cycle modulate the ion beam using the bistable actuators to provide intensity modulation of the ion beam.

19. The method of claim 12 wherein a distance between the extended position and the retracted position is equal to a length of the beam cross-sectional area covered by the modulation element when in the extended position.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2009
From: AL-SADAH, JIHAD; MACKIE, THOMAS R; HILL, PATRICK M
To: WISCONSIN ALUMNI RESEARCH FOUNDATION
Reel/Frame 022884/0827 →
CONFIRMATORY LICENSE Recorded Mar 10, 2009
From: UNIVERSITY OF WISCONSIN MADISON
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 022370/0151 →
Continuity (2)
Provisional Application 60891859 · Feb 27, 2007
Related Publication 20090212231A1 · Aug 27, 2009