IP Library Granted Patent US 8,275,186
Granted Patent B2
US 8,275,186 · App. 11/344,838 · Granted Sep 25, 2012

Method and apparatus for setting a detection threshold in processing medical images

Assignee: Hologic, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,275,186
App. No.
11/344,838
Granted
Sep 25, 2012
Kind
B2
Abstract

An intuitive user interface is provided that allows for selection of an abnormality level in features in a medical image on the basis of graphical depictions of the abnormalities themselves. In one embodiment, the user interface displays realistic images of actual abnormalities in a series ranging from least severe to most severe and the medical practitioner selects the abnormality level by mouse-clicking on one of the images. The user interface then displays an annotated map of suspected abnormalities with annotations only on those suspected abnormalities that are at least as severe as the selected abnormality. In alternative embodiments, the user interface displays stylized images of the abnormalities plotted by the display using mathematical functions. In yet another alternative, the images are hand-drawn images.

Claims (26)

1. A method for determining a threshold for display of regions of interest, the threshold used by a computer aided detection device for analysis of medical images and the method operating on a computer having a display for displaying the medical images, the method comprising:

displaying a plurality of images on the display, each of the images having a different

abnormality selected from a range of different abnormalities that may be observed in an anatomical image on the display,

receiving, from a user interface, a selection of one of the images and an associated selected abnormality, and

displaying, in response to said selected image and associated selected abnormality, an anatomical image in which abnormalities less severe than the selected abnormality are not annotated.

2. The method of claim 1 wherein the abnormalities in the anatomical image are scored to produce a set of scores, said method further comprising:

establishing a threshold having a value that depends on the abnormality of the selected image; and

comparing each score of the set of scores with the threshold to determine which abnormalities to annotate.

3. The method of claim 1 wherein the images are images of actual abnormalities.

4. The method of claim 1 wherein the images are images of actual abnormalities in lung nodules.

5. The method of claim 1 wherein the images are representative of abnormalities.

6. The method of claim 5 wherein the images are generated mathematically.

7. The method of claim 5 wherein the images are hand-drawn.

8. In a system for displaying medical images in which certain abnormalities are annotated, a method comprising:

displaying a plurality of images, each image of the plurality having an abnormality selected from a range of different abnormalities that may be observed in an anatomical image,

receiving, from a user interface, a selection of one of the images having an associated selected abnormality, and

displaying, in response to the selection of the one of the images having the associated selected abnormality, an anatomical image in which abnormalities less severe than the selected abnormality of the selected image are not annotated.

9. The method of claim 8 further comprising:

scoring the abnormalities in the anatomical image to produce a set of scores;

establishing a threshold having a value that depends on which image is selected; and

comparing each score of the set of scores with the threshold to determine which abnormalities to annotate.

10. The method of claim 8 wherein the images are images of actual abnormalities.

11. The method of claim 8 wherein the images are images of actual abnormalities in lung nodules.

12. The method of claim 8 wherein the images are representative of abnormalities.

13. The method of claim 12 wherein the images are generated mathematically.

14. The method of claim 12 wherein the images are hand-drawn.

Assignments (13)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
TERMINATION OF PATENT SECURITY AGREEMENTS AND RELEASE OF SECURITY INTERESTS Recorded Aug 26, 2010
From: GOLDMAN SACHS CREDIT PARTNERS, L.P., AS COLLATERAL AGENT
To: HOLOGIC, INC.; R2 TECHNOLOGY, INC.; SUROS SURGICAL SYSTEMS, INC.; BIOLUCENT, LLC; DIRECT RADIOGRAPHY CORP.; CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP; CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS III, INC.; CYTYC PRENATAL PRODUCTS CORP.; THIRD WAVE TECHNOLOGIES, INC.
Reel/Frame 024892/0001 →
21ST SUPPLEMENT TO PATENT SECURITY AGREEMENT Recorded Mar 29, 2010
From: HOLOGIC, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
Reel/Frame 024151/0435 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 8, 2009
From: R2 TECHNOLOGY, INC.
To: HOLOGIC, INC.
Reel/Frame 023620/0362 →
PATENT SECURITY AGREEMENT Recorded Jul 29, 2008
From: R2 TECHNOLOGY, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
Reel/Frame 021301/0838 →
PATENT SECURITY AGREEMENT Recorded Oct 26, 2007
From: R2 TECHNOLOGY, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P.
Reel/Frame 020024/0231 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2006
From: RAFFY, PHILIPPE
To: R2 TECHNOLOGY, INC.
Reel/Frame 017598/0094 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2006
From: RAFFY, PHILIPPE
To: R2 TECHNOLOGY, INC.
Reel/Frame 017536/0320 →
Continuity (1)
Related Publication 20070177782A1 · Aug 2, 2007