Implants having high fatigue resistance, implant delivery systems, and methods of use

1. A stent for implant in a mammalian body comprising:

a tubular structure having an inside diameter, an outside diameter, a sidewall therebetween, a central axis defining a longitudinal direction, and apertures extending through the sidewall, wherein said sidewall is a circumferential sidewall having a wall thickness, said apertures separating struts joined at apices, said apices having a structure to exhibit a level of tensile strain, said struts being generally longitudinally extending and having different widths with a plurality of the struts grouped to define a cell, wherein in the circumferential direction of the stent, each cell comprises a first group of struts having a first width and a second group of struts having a second width different from the first width, with apices that are adjacent in the circumferential direction being offset with respect to one another in the longitudinal direction, said stent having a length along the central axis, wherein elongation of the stent in the longitudinal direction causes a change in the level of tensile strain in the apices, wherein said stent is structured such that when elongated at least 10%, the level of tensile strain in each apex is less than about 3%.

2. The stent of claim 1 , wherein when the stent is elongated at least 10%, the level of tensile strain in each apex is less than about 2%.

3. The stent of claim 1 , wherein when the stent is elongated at least 20%, the level of tensile strain in each apex is less than about 3%.

4. The stent of claim 1 , wherein when the stent is elongated at least 30%, the level of tensile strain in each apex is less than about 3%.

5. The stent of claim 1 , wherein when the stent is elongated at least 40%, the level of tensile strain in each apex is less than about 3%.

6. The stent of claim 1 , wherein when the stent is elongated at least 50%, the level of tensile strain in each apex is less than about 3%.

7. The stent of claim 1 , wherein a tolerance level of tensile strain in each apex is about ±0.5%.

8. The stent of claim 1 , wherein at least some of said apices are opposed to one another when the stent is in an unexpanded configuration and are circumferentially offset from one another when the stent is in an expanded configuration.

9. The stent of claim 1 , wherein said tubular structure comprises a laser cut tube.

10. The stent of claim 1 , wherein said tubular structure comprises a wire joined at regions to form said struts and said apices.

11. The stent of claim 1 , wherein said tubular structure comprises a braid.

12. The stent of claim 1 , wherein the first group comprises three struts and the second group comprises five struts.

13. The stent of claim 12 , wherein adjacent cells are joined together in the circumferential direction by connecting a first strut of the first group to a last strut of the second group, as viewed in the circumferential direction.

14. The stent of claim 12 , wherein the struts in the first group have a smaller width and a smaller length than the struts in the second group.

15. The stent of claim 12 , wherein the struts in the first group have a greater width and a greater length than the struts in the second group.

16. The stent of claim 1 , wherein the apices of the first group have a different width than the apices of the second group.

17. The stent of claim 1 , wherein the second width is different from the first width by about 20%.

18. The stent of claim 1 , wherein the second width is different from the first width by about 10%.

19. The stent of claim 1 , wherein the first group of struts has a length that is different from a length of the second group of struts.