IP Library Granted Patent US 8,396,561
Granted Patent B2
US 8,396,561 · App. 12/520,741 · Granted Mar 12, 2013

Visual prosthesis and methods of creating visual perceptions

Inventors: John S. Pezaris (Cambridge, MA); R. Clay Reid (Cambridge, MA); Emad N. Eskandar (Nahant, MA)
Assignees: The General Hospital Corporation; President and Fellows of Harvard College
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Quick Facts
Patent No.
US 8,396,561
App. No.
12/520,741
Granted
Mar 12, 2013
Kind
B2
Abstract

A visual prosthesis and methods of allowing a subject to view visual information from an artificial source are provided. The visual prosthesis has one or more electrodes operative to deliver electrical signals to a lateral geniculate nucleus of a mammal, a power supply operative to provide power to the electrodes, a visual information translator operatively connected to the electrode array, and a visual sensor operatively connected to the visual information translator. The visual prosthesis is operative to translate visual information into an electrical signal and transmit the electrical signal to electrodes to stimulate brain activity to recognize visual information.

Claims (25)

1. A method of providing a mammal with visual information from an artificial source, comprising;

operatively connecting one or more electrodes to a lateral geniculate nucleus of the mammal;

providing visual information from said artifical source;

translating the visual information into an electrical signal;

transmitting the electrical signal to the electrodes; and

stimulating the lateral geniculate nucleus with the electrical signal through the electrodes in a manner to stimulate brain activity to recognize visual information.

2. The method of claim 1 , further comprising creating a map of the electrode connected to the lateral geniculate nucleus.

3. The method of claim 1 , wherein the visual information is hyperacute.

4. The method of claim 1 , further comprising reading the position of an eye of the mammal to provide gaze information, wherein the gaze information determines the origin of visual information.

5. The method of claim 1 , further comprising transmitting electrical power to the electrodes.

6. The method of claim 1 , wherein the electrodes are of differing length.

7. The method of claim 1 , wherein the electrodes are made of glial cells, cultured neurons, nerve bundles, copper, tungsten, titanium, platinum/iridium, insulated metallic wires, carbon, boron, silicon, or conductive fibers.

8. The method of claim 7 , wherein the electrodes are coated with a biocompatible insulating surface comprising Teflon, parlene, formvar, silicone, native oxide, or a combination thereof.

9. The method of claim 1 , wherein the electrodes are biological.

10. The method of claim 1 , wherein the electrodes comprise electrically controlled neurons synapsing onto the lateral geniculate nucleus.

11. The method of claim 1 , wherein the electrodes have a source of electrical power.

12. The method of claim 1 , wherein the electrical signal comprises repetitive pulse waveforms.

13. The method of claim 12 , wherein the repetitive waveforms are square waves, sinusoidal pulses, triangle waves, or square pulses.

14. The method of claim 1 , wherein the electrical signal comprises patterned waveforms.

15. The method of claim 1 , further comprising penetrating each layer of the lateral geniculate nucleus with at least one electrode.

16. The method of claim 1 , further comprising penetrating each lateral geniculate nucleus with at least one electrode.

17. The method of claim 1 , further comprising penetrating each layer of each lateral geniculate nucleus with at least one electrode.

18. The method of claim 1 , wherein the electrical signals are transmitted wirelessly to the electrodes.

19. The method of claim 1 , wherein the electrical signals are transmitted via biological leads to the electrodes.

20. The method of claim 1 , wherein the electrical signals are transmitted via wire leads to the electrodes.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2013
From: ESKANDAR, EMAD N.
To: GENERAL HOSPITAL CORPORATION
Reel/Frame 029741/0730 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 11, 2009
From: PEZARIS, JOHN S.; REID, R. CLAY
To: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Reel/Frame 023642/0181 →
CONFIRMATORY LICENSE Recorded Aug 10, 2009
From: GENERAL HOSPITAL CORPORATION DBA MASS
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 023071/0105 →
Continuity (2)
Provisional Application 60876837 · Dec 22, 2006
Related Publication 20100094382A1 · Apr 15, 2010