Substituted 1-benzyl-cinnolin-4(1

1. A compound of formula (I):

wherein:

R 1 represents:

a phenyl which is unsubstituted or substituted one or more times by substituents chosen independently from a halogen atom, an Alk group, an OAlk group, a cyano, an —NH SO 2 Alk group and an —SO 2 Alk group;

a naphthyl which is unsubstituted or substituted one or more times by substituents chosen independently from a halogen atom, an Alk group and an OAlk group;

a pyridyl which is unsubstituted or substituted one or more times by substituents chosen independently from a halogen atom, an Alk group and an OAlk group;

a 1-benzothienyl which is unsubstituted or substituted one or more times by substituents chosen independently from a halogen atom, an Alk group and an OAlk group; or

a 1,3-benzodioxolyl which is unsubstituted or substituted one or more times by substituents chosen independently from a halogen atom, an Alk group and an OAlk group;

R 2 represents:

a phenyl which is unsubstituted or substituted once or twice by substituents chosen independently from a halogen atom, an Alk group and a cyano; or

a thienyl or a pyridyl, each of which is substituted by a halogen atom or an Alk group;

R 3 represents a hydrogen atom, a halogen atom, an Alk group or an OAlk group; and

Alk represents a (C 1 -C 4 )alkyl which is unsubstituted or substituted one or more times by a fluorine atom;

or an acid addition salt thereof.

2. The compound according to claim 1 , wherein:

R 1 represents:

a phenyl which is unsubstituted or substituted once or twice by substituents chosen independently from a halogen atom, an Alk group, an OAlk group and an —SO 2 Alk group;

a naphthyl;

a pyridyl substituted by an Alk group or an OAlk group;

a 1-benzothienyl; or

a 1,3-benzodioxolyl substituted by one or more fluorine atoms; and

R 3 represents a hydrogen or halogen atom or an OAlk group;

or an acid addition salt thereof.

3. The compound according to claim 1 , wherein:

R 1 represents:

a phenyl, a 4-chlorophenyl, a 2-fluorophenyl, a 3-fluorophenyl, a 2-methylphenyl, a 4-methylphenyl, a 3-isopropylphenyl, a 2-trifluoromethylphenyl, a 3-trifluoromethylphenyl, a 2-methoxyphenyl, a 4-methoxyphenyl, a 2-trifluoromethoxyphenyl, a 3-trifluoromethoxyphenyl, a 4-trifluoromethoxyphenyl, a 2,3-dichlorophenyl, a 3,5-dichlorophenyl, a 2,3-difluorophenyl, a 2,5-difluorophenyl, a 3-chloro-2-fluorophenyl, a 2-chloro-3-trifluoromethylphenyl, a 3-chloro-5-trifluoromethylphenyl, a 4-chloro-2-trifluoromethylphenyl, a 3-bromo-2-fluorophenyl, a 2-fluoro-3-methylphenyl, a 2-fluoro-4-methylphenyl, a 2-fluoro-3-trifluoromethylphenyl, a 3-fluoro-2-trifluoromethylphenyl, a 3-fluoro-5-trifluoromethylphenyl, a 3-fluoro-2-methoxyphenyl, a 4-fluoro-2-methoxyphenyl, a 2-fluoro-5-trifluoromethoxyphenyl, a 3-isopropyl-6-methoxyphenyl, a 3-(tert-butyl)-6-methoxyphenyl, a 2-(methylsulphonyl)phenyl;

a naphthyl;

a 2-methoxypyrid-5-yl, a 2-trifluoromethylpyrid-3-yl;

a benzothien-2-yl, a benzothien-7-yl; or

a 2,2-difluorobenzodioxol-4-yl;

R 2 represents:

a phenyl, a 4-chlorophenyl, a 2-fluorophenyl, a 4-fluorophenyl, a 2,4-dichlorophenyl, a 2,4-difluorophenyl, a 2-chloro-4-fluorophenyl, a 4-chloro-2-fluorophenyl, a 2-fluoro-4-methylphenyl, a 2-fluoro-4-trifluoromethylphenyl or a 2-fluoro-4-cyanophenyl;

a 2-chlorothien-5-yl, a 3-trifluoromethylpyrid-6-yl, a 5-chloropyrid-2-yl or a 3,5-difluoropyrid-2-yl; and

R 3 represents a hydrogen atom, a chlorine atom or a methoxy;

or an acid addition salt thereof.

4. The compound according to claim 1 , which is:

1-(2,4-difluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]-8-methoxycinnolin-4(1H)-one;

3-[2-chloro-3-(trifluoromethyl)phenyl]-1-(2,4-difluorobenzyl)-8-methoxycinnolin-4(1H)-one;

3-[2-chloro-3-(trifluoromethyl)phenyl]-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

3-(2,3-dichlorophenyl)-1-(2,4-difluorobenzyl)-8-methoxycinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[3-fluoro-2-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(4-chloro-2-fluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(3-isopropylphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[3-fluoro-2-(trifluoromethyl)phenyl]-8-methoxycinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-8-methoxy-3-[3-(trifluoromethoxy)phenyl]cinnolin-4(1H)-one;

4-{[3-(2,3-dichlorophenyl)-4-oxocinnolin-1(4H)-yl]methyl}-3-fluorobenzonitrile;

3-fluoro-4-({3-[2-fluoro-3-(trifluoromethyl)phenyl]-4-oxocinnolin-1 (4H)-yl}methyl)benzonitrile;

1-(2,4-difluorobenzyl)-3-(4-fluoro-2-methoxyphenyl)cinnolin-4(1H)-one;

3-(2,3-dichlorophenyl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(5-fluoro-2-methoxyphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(2-methoxyphenyl)cinnolin-4(1H)-one;

3-(3-bromo-2-fluorophenyl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(2-fluoro-3-methylphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[2-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[2-(trifluoromethoxy)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[3-(trifluoromethoxy)phenyl]cinnolin-4(1H)-one;

1-(2-chloro-4-fluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(4-chloro-2-fluorobenzyl)-3-(5-fluoro-2-methoxyphenyl)cinnolin-4(1H)-one;

3-(3-chloro-2-fluorophenyl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

3-fluoro-4-({4-oxo-3-[2-(trifluoromethyl)phenyl]cinnolin-1(4H)-yl}methyl)benzonitrile;

1-(2,4-difluorobenzyl)-3-(4-methylphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-[(5-chlorothien-2-yl)methyl]-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[2-(trifluoromethyl)pyridin-3-yl]cinnolin-4(1H)-one;

3-(1-benzothien-7-yl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

1-benzyl-3-(3-isopropylphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(5-isopropyl-2-methoxyphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(1-naphthyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[2-(trifluoromethyl)pyridin-3-yl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[2-fluoro-5-(trifluoromethoxy)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(4-methoxyphenyl)cinnolin-4(1H)-one;

3-(2,2-difluoro-1,3-benzodioxol-4-yl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

3-(4-chlorophenyl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

1-[(5-chlorothien-2-yl)methyl]-3-(2,3-dichlorophenyl)cinnolin-4(1H)-one;

1-(4-chloro-2-fluorobenzyl)-3-[3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(4-fluorobenzyl)-3-(5-fluoro-2-methoxyphenyl)cinnolin-4(1H)-one;

1-(2-fluoro-4-methylbenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2-fluorobenzyl)-3-(5-fluoro-2-methoxyphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(2-fluoro-4-methylphenyl)cinnolin-4(1H)-one;

1-(4-fluorobenzyl)-3-[3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(3-fluorophenyl)cinnolin-4(1H)-one;

3-(5-fluoro-2-methoxyphenyl)-1-[2-fluoro-4-(trifluoromethyl)benzyl]cinnolin-4(1H)-one;

1-(4-fluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

3-(5-fluoro-2-methoxyphenyl)-1-(2-fluoro-4-methylbenzyl)cinnolin-4(1H)-one;

1-(2-chloro-4-fluorobenzyl)-3-(5-fluoro-2-methoxyphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(2,5-difluorophenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[3-fluoro-5-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(2-methylphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(2-naphthyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(2,3-difluorophenyl)cinnolin-4(1H)-one;

1-[2-fluoro-4-(trifluoromethyl)benzyl]-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

3-[3-chloro-5-(trifluoromethyl)phenyl]-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

3-(3,5-dichlorophenyl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(2-fluorophenyl)cinnolin-4(1H)-one;

1-(2,4-dichlorobenzyl)-3-(5-fluoro-2-methoxyphenyl)cinnolin-4(1H)-one;

3-[2-fluoro-3-(trifluoromethyl)phenyl]-1-{[5-(trifluoromethyl)pyridin-2-yl]methyl}cinnolin-4(1H)-one;

3-(5-(tert-butyl)-2-methoxyphenyl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

1-[2-fluoro-4-(trifluoromethyl)benzyl]-3-[3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

3-[4-chloro-2-(trifluoromethyl)phenyl]-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(5-fluoro-2-hydroxyphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-phenylcinnolin-4(1H)-one;

1-(2,4-dichlorobenzyl)-3-[3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2-chloro-4-fluorobenzyl)-3-[3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2-fluoro-4-methylbenzyl)-3-[3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

3-(1-benzothien-2-yl)-1-(4-chlorobenzyl)cinnolin-4(1H)-one;

1-(2-fluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-[(5-chlorothien-2-yl)methyl]-3-(5-fluoro-2-methoxyphenyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[4-(trifluoromethoxy)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-(6-methoxypyridin-3-yl)cinnolin-4(1H)-one;

3-(2,3-dichlorophenyl)-1-{[5-(trifluoromethyl)pyridin-2-yl]methyl}cinnolin-4(1H)-one;

7-chloro-1-(2,4-difluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[3-fluoro-2-(trifluoromethyl)phenyl]-7-methoxycinnolin-4(1H)-one;

7-chloro-3-[2-chloro-3-(trifluoromethyl)phenyl]-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-7-methoxy-3-[3-(trifluoromethoxy)phenyl]cinnolin-4(1H)-one;

4-({3-[2-chloro-3-(trifluoromethyl)phenyl]-4-oxocinnolin-1(4H)-yl}methyl)-3-fluorobenzonitrile;

7-chloro-1-(2,4-difluorobenzyl)-3-[3-fluoro-2-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

7-chloro-3-(2,3-dichlorophenyl)-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

7-chloro-1-(2,4-difluorobenzyl)-3-[3-(trifluoromethoxy)phenyl]cinnolin-4(1H)-one;

7-chloro-1-(2,4-difluorobenzyl)-3-[2-(methylsulphonyl)phenyl]cinnolin-4(1H)-one;

1-[(5-chloropyridin-2-yl)methyl]-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

6-chloro-3-[2-chloro-3-(trifluoromethyl)phenyl]-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one;

6-chloro-1-(2,4-difluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

1-(2,4-difluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]-6-methoxycinnolin-4(1H)-one; or

6-chloro-1-[(3,5-difluoropyridin-2-yl)methyl]-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one;

or an acid addition salt thereof.

5. A pharmacetucial composition comprising the compound according to claim 1 , or an acid addition salt thereof, and at least one pharmaceutically acceptable excipient.

6. A pharmacetucial composition comprising the compound according to claim 2 , or an acid addition salt thereof, and at least one pharmaceutically acceptable excipient.

7. A pharmacetucial composition comprising the compound according to claim 3 , or an acid addition salt thereof, and at least one pharmaceutically acceptable excipient.

8. A pharmacetucial composition comprising the compound according to claim 4 , or an acid addition salt thereof, and at least one pharmaceutically acceptable excipient.

9. A process for preparing the compound of formula (I) according to claim 1 , comprising:

reacting a compound of formula:

wherein R 2 and R 3 are as defined in claim 1 , in the presence of a base, with a compound of formula (III):

R 1 —B(OH) 2   (III)

wherein R 1 is as defined in claim 1 .