Device and method for controlling injection of liquid embolic composition
A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.
1. A liquid embolic delivery system comprising:
a catheter having a lumen for delivery of a liquid embolic composition including a solvent to a cavity;
a containment member positioned at a distal end of the catheter, the containment member shaped to trap the liquid embolic composition delivered through the lumen of the catheter, the containment member being permeable to the solvent of the liquid embolic composition to allow the solvent to dissipate from the liquid embolic composition; and
a detachment mechanism for completely detaching the containment member from the catheter after solidification of the liquid embolic composition to allow separation of the catheter from a mass of solidified embolic composition.
2. The liquid embolic delivery system according to claim 1 , wherein the containment member is a flexible sack which fills with the liquid embolic composition.
3. The liquid embolic delivery system according to claim 2 , wherein the flexible sack is positioned over a distal outlet of the lumen with a neck of the sack connected to the distal end of the catheter around an opening of the catheter lumen, the detachment mechanism detaching the flexible sack neck from the distal end of the catheter.
4. The liquid embolic delivery system according to claim 2 , wherein the flexible sack is formed of a mesh material which allows solvent to pass through the sack, the mesh material containing the liquid embolic composition which has solidified.
5. The liquid embolic delivery system according to claim 2 , wherein the flexible sack is formed as a resilient balloon over the distal end of the catheter.
6. The liquid embolic delivery system according to claim 1 , wherein the containment member is a nidus extending from the distal end of the catheter and positioned to trap the liquid embolic composition as the liquid embolic composition solidifies.
7. The liquid embolic delivery system according to claim 6 , wherein the nidus is formed from a wire which is delivered through the catheter lumen and forms a coil upon exiting the distal end of the lumen.
8. The liquid embolic delivery system according to claim 6 , wherein the nidus is in the form of a wire brush.
9. The liquid embolic delivery system according to claim 6 , wherein the nidus is in the form of a swab.
10. The liquid embolic delivery system according to claim 6 , wherein the nidus is in the form of a flexible sack.
11. The liquid embolic delivery system according to claim 6 , wherein the nidus is formed from a wire which is delivered through the catheter lumen and forms a randomly shaped nest upon exiting the distal end of the lumen.
12. The liquid embolic delivery system according to claim 1 , wherein the detachment mechanism includes means for delivering an electrical charge to a point between the containment member and the catheter to detach the containment member from the catheter.
13. The liquid embolic delivery system according to claim 1 , wherein the detachment mechanism includes a chemical detachment section between the containment member and the catheter which is dissolved by a chemical agent.
14. A liquid embolic delivery system comprising:
a catheter having a lumen for delivery of a liquid embolic composition to a cavity;
a containment member positioned at a distal end of the catheter, the containment member shaped to trap the liquid embolic composition delivered through the lumen of the catheter; and
a detachment mechanism for completely detaching the containment member from the catheter after solidification of the liquid embolic composition to allow separation of the catheter from a mass of solidified embolic composition, wherein the containment member is a nidus extending from the distal end of the catheter and positioned to trap the liquid embolic composition as the liquid embolic composition solidifies, wherein the nidus is in the form of a sponge.