IP Library Granted Patent US 8,509,901
Granted Patent B2
US 8,509,901 · App. 11/526,949 · Granted Aug 13, 2013

Device and method for adding to breathing

Inventor: Amir J. Tehrani (San Francisco, CA)
Assignee: RMX, LLC
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Quick Facts
Patent No.
US 8,509,901
App. No.
11/526,949
Granted
Aug 13, 2013
Kind
B2
Abstract

A method and device is provided for adding to breathing by stimulating tissue to elicit a diaphragm response during intrinsic breathing.

Claims (21)

1. A method of treating a breathing disorder of a patient, comprising:

sensing a respiratory parameter of the patient;

comparing the sensed respiratory parameter against a threshold level via the stimulator coupled thereto, wherein the threshold level is above the level of the respiratory parameter when respiration ceases;

when the respiratory parameter meets the threshold level and is indicative of a breathing disorder, electrically stimulating a phrenic nerve or diaphragm tissue with an electrical stimulation signal via the stimulator to adjust a respiratory parameter of the patient, where the electrical stimulation signal comprises a burst or series of pulses; and

activating at least a portion of the diaphragm via the electrical stimulation signal for a time and at a level effective to further control or manage pulmonary stretch receptor threshold levels to maintain upper airway patency.

2. The method of claim 1 wherein sensing a respiratory parameter comprises sensing the respiratory parameter via at least one or more electrodes in electrical communication with the phrenic nerve or diaphragm tissue.

3. The method of claim 1 wherein the stimulator adjusts the respiratory parameter of the patient to elicit an increased inspiration volume with respect to an intrinsic inspiration volume of the sensed respiratory parameter.

4. The method of claim 1 wherein the stimulator adjusts the respiratory rate of the patient to elicit a decreased exhalation volume with respect to an intrinsic exhalation volume of the sensed respiratory rate.

5. The method of claim 1 wherein the stimulator adjusts the respiratory rate of the patient to elicit a decreased exhalation duration with respect to an intrinsic exhalation duration of the sensed respiratory rate.

6. The method of claim 1 wherein the stimulator adjusts the respiratory rate of the patient to elicit an inspiration rate different from an intrinsic inspiration rate.

7. The method of claim 1 wherein the stimulator adjusts the respiratory rate of the patient to elicit an exhalation rate different from an intrinsic exhalation rate.

8. A device for treating a breathing disorder of a patient comprising:

at least one electrode in electrical communication with a diaphragm or phrenic nerve tissue of a patient's body;

a control unit in electrical communication with the at least one electrode whereby the control unit receives respiration activity sensed by at the least one electrode,

wherein the control unit is programmed to generate an electrical stimulation signal in response to the sensed respiration, programmed with a threshold level of a respiratory parameter, wherein the threshold level being above the level of the respiration activity when respiration ceases, and programmed to deliver the electrical stimulation signal comprising a burst or series of pulses if the sensed respiration activity meets the threshold level and indicates a breathing disorder to adjust the breathing cycle of said patient, said electrical stimulation signal delivered through the at least one electrode to the diaphragm or phrenic nerve tissue, and

wherein the electrical stimulation signal is configured to activate at least a portion of the diaphragm and to further control or manage pulmonary stretch receptor threshold levels to maintain upper airway patency.

9. The device of claim 8 wherein the control unit is further programmed to deliver a stimulation signal to the tissue through the at least one electrode to elicit an increased inspiration volume with respect to the intrinsic inspiration volume of the intrinsic breath.

10. The device of claim 8 wherein the control unit is further programmed to deliver a stimulation signal to the tissue through the at least one electrode to elicit a decreased exhalation volume with respect to an intrinsic exhalation volume of the intrinsic breath.

11. The device of claim 8 wherein the control unit is further programmed to deliver a stimulation signal to the tissue through the at least one electrode to elicit a decreased exhalation duration with respect to an intrinsic exhalation duration of the intrinsic breath.

12. The device of claim 8 wherein the control unit is further programmed to deliver a stimulation signal to the tissue through the at least one electrode to elicit an inspiration rate different from an intrinsic inspiration rate.

13. The device of claim 8 wherein the control unit is further programmed to deliver a stimulation signal to the tissue through the at least one electrode to elicit an exhalation rate different from an intrinsic exhalation rate.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 14, 2007
From: INSPIRATION MEDICAL, INC.
To: RMX, L.L.C.
Reel/Frame 020266/0533 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2007
From: TEHRANI, AMIR J.
To: INSPIRATION MEDICAL, INC.
Reel/Frame 019421/0953 →
Continuity (2)
Continuation 10686891 · Oct 15, 2003
Related Publication 20070021795A1 · Jan 25, 2007