Film-coated scored tablet
A film-coated scored tablet in which the forms of respective parts associated with a score line are optimized so as to more preferably divide the film along the score line is provided.
1. A film-coated scored tablet comprising a tablet being coated with a film coating on a plain tablet having score lines, wherein
the scored tablet has an upper surface and a lower surface whose peripheral shape is an oval shape, and a peripheral side surface, the upper surface and the lower surface are gradually elevated from the peripheral edge toward the center thereof, and a V-shaped groove as the score line is provided on each of the upper surface and the lower surface along the minor axis of the oval shape;
an inner angle of the V shape of the V-shaped groove is from 50° to 90°;
a path of the bottom of the V-shaped groove is elevated more on the center side than on the peripheral edge sides of each of the upper surface and the lower surface;
a ratio of a depth d of the V-shaped groove in the center of each of the upper surface and the lower surface to a height h of the elevation of the surface (d/h) is from 0.4 to 0.9; and
a ratio of a value obtained by doubling the depth d of the V-shaped groove (2d) in the center of each of the upper surface and the lower surface to a total thickness t of the scored tablet (2d/t) is from 0.2 to 0.4.
2. The film-coated scored tablet according to claim 1 , wherein the oval shape is an oval shape which does not have straight-line portions.
3. The film-coated scored tablet according to claim 1 , wherein a ratio of the diameter of the minor axis S to the diameter of the major axis L (S/L) of the oval shape is from 0.4 to 0.6.
4. The film-coated scored tablet according to claim 1 , wherein the diameter of the major axis L of the oval shape is from 8 mm to 12 mm.
5. The film-coated scored tablet according to claim 1 , wherein the inner angle of the V shape of the V-shaped groove is 70°.
6. The film-coated scored tablet according to claim 1 , wherein the depth d is from 0.5 to 0.8 mm.
7. The film-coated scored tablet according to claim 1 , wherein a bending strength represented by a force required for dividing the film-coated scored tablet when the force is applied thereto so as to divide the tablet at the score line is 50 N or less.
8. The film-coated scored tablet according to claim 1 , which contains 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile or a salt thereof.
9. The film-coated scored tablet according to claim 1 , which contains 2-ethoxy-1-[[2′-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid or a salt thereof.