Cartridge device for blood analysis
A cartridge device having a receiving portion for receiving a blood sample and a jack portion for receiving a plug; a stirring device for circulating the blood sample within the receiving portion; and an electrode holder having at least one incorporated electrode wire pair; wherein the electrode holder is attachable to the cell such that one end of the at least one electrode wire pair forms a sensor unit for measuring the electrical impedance between the two electrode wires of the at least one electrode wire pair within the blood sample and that the opposite end of the at least one electrode wire pair forms a plug portion being connectable directly to the plug for an electrical connection of the sensor unit to an analyzer.
1. A cartridge device for conducting platelet aggregation analysis, comprising:
a cell having a receiving portion for receiving a blood sample;
a stirring device for circulating said blood sample within said receiving portion;
an electrode holder having at least two sensor units, wherein each sensor unit comprises at least two electrodes for measuring the electrical impedance between the at least two electrodes within the blood sample in at least two different locations; and
an analyser for comparing the electrical impedances measured by each one of the at least two sensor units in each of the at least two different locations in the blood sample in order to determine whether an acceptable or a non-acceptable variation in the impedance measurements exists, wherein the analyser stops an analysis of platelet aggregation when a non-acceptable variation is indicated, and reports a mean value of the impedance measurements by the at least two sensor units when an acceptable variation is indicated;
wherein the electrode holder is attached to the cell such that one end of each one of the at least two electrodes forming one of the sensor units for measuring the electrical impedance between the at least two electrodes is within the blood sample and that the opposite end of each one of the at least two electrodes is connectable to the analyser;
wherein the at least two electrodes consist of a metal comprising a first material comprising at least one of copper and copper alloy, which is covered by a second material comprising at least one of silver, platinum, and gold.
2. The cartridge device according to claim 1 , wherein the first material is a copper-silver alloy.
3. The cartridge device according to claim 2 , wherein the copper-silver alloy comprises 0.2 to 2% silver.
4. The cartridge device according to claim 2 , wherein the copper-silver alloy comprises 0.9% silver.
5. The cartridge device according to claim 1 , wherein the second material is a silver coating with a mass coverage in the range of 0.5 to 20 g/kg.
6. The cartridge device according to claim 1 , wherein the second material is a silver coating with a mass coverage of about 2 g/kg.
7. The cartridge device according to claim 1 , wherein the at least two electrodes stand out of the electrode holder between 2 mm and 6 mm.
8. The cartridge device according to claim 1 , wherein the at least two electrodes have a spacing between them of between 0.5 mm and 1 mm.
9. A cartridge device for conducting platelet aggregation analysis, comprising:
a cell having a receiving portion for receiving a blood sample;
a stirring device for circulating said blood sample within said receiving portion;
an electrode holder having at least two sensor units, wherein each sensor unit comprises at least two electrodes for measuring the electrical impedance in the blood sample in at least two different locations; and
an analyser for comparing the electrical impedances measured by each one of the at least two sensor units in each of the at least two different locations in the blood sample in order to determine whether an acceptable or a non-acceptable variation in the impedance measurements exists, wherein the analyser stops an analysis of platelet aggregation when a non-acceptable variation is indicated, and reports a mean value of the impedance measurements by the at least two sensor units when an acceptable variation is indicated;
wherein the electrode holder is attached to the cell such that one end of the at least two electrodes forming one of the at least two sensor units for measuring the electrical impedance between the at least two electrodes within is in the blood sample and that the opposite end of the at least two electrodes is connectable to the analyser;
wherein the at least two electrodes consist of a metal comprising a first material comprising at least one of copper and copper alloy, which is covered by a second material comprising at least one of silver, platinum and gold; and
wherein the at least two electrodes stand out of the electrode holder between 2 mm and 6 mm.
10. The cartridge device according to claim 9 , wherein the first material is a copper-silver alloy.
11. The cartridge device according to claim 10 , wherein the copper-silver alloy comprises 0.2% to 2% silver.
12. The cartridge device according to claim 10 , wherein the copper-silver alloy comprising 0.9% silver.
13. The cartridge device according to claim 9 , wherein the second material is a silver coating with a mass coverage in the range of 0.5 to 20 g/kg.
14. The cartridge device according to claim 9 , wherein the second material is a silver coating with a mass coverage of about 2 g/kg.
15. The cartridge device according to claim 9 , wherein the at least two electrodes have a circular cross section and have a diameter between 0.1 mm and 0.50 mm.
16. The cartridge device according to claim 9 , wherein the at least two electrodes have a spacing between them of between 0.5 mm and 1 mm.
17. A cartridge device for conducting platelet aggregation analysis, comprising:
a cell having a receiving portion for receiving a blood sample;
a stirring device for circulating said blood sample within said receiving portion;
an electrode holder having at least two sensor units, wherein each sensor unit comprises at least two electrodes for measuring the electrical impedance in the blood sample in at least two different locations; and
an analyser for comparing the electrical impedances measured by each one of the at least two sensor units in each of the at least two different locations in the blood sample in order to determine whether an acceptable or a non-acceptable variation in the impedance measurements exists, wherein the analyser stops an analysis of platelet aggregation when a non-acceptable variation is indicated, and reports a mean value of the impedance measurements by the at least two sensor units when an acceptable variation is indicated;
wherein the electrode holder is attached to the cell such that one end of the at least two electrodes forming one of the at least two sensor units for measuring the electrical impedance between the at least two electrodes within the blood sample and that the opposite end of the at least two electrodes is connectable to the analyser;
wherein the at least two electrodes consist of a metal comprising a first material comprising at least one of copper and copper alloy, which is covered by a second material comprising at least one of silver, platinum and gold; and
wherein the at least two electrodes have a spacing between them of between 0.5 mm and 1 mm.
18. The cartridge device according to claim 17 , wherein the first material is a copper-silver alloy, and wherein the copper-silver alloy comprises 0.2% to 2% silver.
19. The cartridge device according to claim 17 , wherein the second material is a silver coating with a mass coverage in the range of 0.5 to 20 g/kg.
20. The cartridge device according to claim 17 , wherein the at least two electrodes have a circular cross section and have a diameter between 0.1 mm and 0.50 mm.
21. The cartridge device according to claim 17 , wherein the at least two electrodes stand out of the electrode holder between 2 mm and 6 mm.