Device with penetrable and resealable portion and related method
Device and method for needle penetrating and filling a chamber with a predetermined substance, and hermetically resealing a resulting needle hole in the device by applying radiation thereto. The needle penetrable and resealable portion defines a predetermined wall thickness in an axial direction thereof, and may include a thermoplastic that substantially prevents the formation of particles released into the chamber from the needle penetrable and resealable portion during penetration by and withdrawal of the needle. Such thermoplastic may include a predetermined amount of pigment that allows the thermoplastic to substantially absorb laser radiation at a predetermined wavelength, substantially prevent the passage of radiation through the predetermined wall thickness thereof, and hermetically seal a needle aperture formed in the needle penetration region thereof in a predetermined time period.
1. A resealable closure member for closing a device defining a chamber for receiving a substance therein, the closure member comprising a resealable elastomer material comprising a styrene copolymer thermoplastic elastomer with a colorant to have an absorption of laser radiation at a wavelength of approximately 980 nm in an amount to absorb said laser radiation and reseal a penetration aperture in the closure member formed by penetration therethrough of a needle, filling member or injection member.
2. The closure member of claim 1 , wherein said device is a vial or a syringe.
3. The closure member of claim 1 , wherein the colorant comprises pigment mixed with a carrier material.
4. The closure member of claim 3 , wherein said pigment has a grey color.
5. The closure member of claim 4 , wherein the colorant comprises black pigment.
6. The closure member of claim 3 , wherein the colorant comprises 11.17 wt. % pigment, the balance up to 100% comprising the carrier material.
7. The closure member of claim 3 , wherein the elastomer material comprises about 2.65-5.30 wt. % of colorant, the balance up to 100% comprising the thermoplastic elastomer.
8. The closure member of claim 7 , wherein the elastomer material comprises about 3 wt. % of colorant, the balance up to 100% comprising the thermoplastic elastomer.
9. The closure member of claim 3 , wherein the elastomer material has a thickness that is sufficient to substantially prevent laser power of about 8 Watts incident power from passing therethrough.
10. The closure member of claim 1 , wherein absorbed radiation is converted to heat.