Granted Patent B2

US 8,700,145 · App. 13/651,349 · Granted Apr 15, 2014

Inventors: Michael P. Kilgard (Richardson, TX); Navzer Engineer (Plano, TX); David Michael Pierce (Plano, TX); Robert L. Rennaker (Sachse, TX)

Assignees: MicroTransponder, Inc.; The Board of Regents, The University of Texas System

Abstract

Claims (26)

1. A method of improving motor deficits in a stroke patient, comprising:

assessing a stroke patient's motor deficits;

determining therapeutic goals for the patient, based on the patient's motor deficits;

selecting one or more therapeutic tasks based on the therapeutic goals;

observing repetitive performances by the patient of the selected therapeutic task;

stimulating the vagus nerve of the patient with an implanted neurostimulator that delivers pulse trains of electrical stimulation energy to a vagus nerve while the patient is performing a movement of the selected therapeutic task;

terminating the stimulation of the vagus nerve so that there is no stimulation between movement execution; and

improving the patient's motor deficits,

wherein the action of stimulating the vagus nerve of the patient further comprises determining respective beginnings of performances of the selected therapeutic task, and applying the pulse trains to the vagus nerve based on the determined beginnings of the performances, and

wherein the stimulation pulse trains begin after the beginning of the respective selected therapeutic tasks, wherein the vagus nerve stimulation pulse trains end prior to the end of the respective selected therapeutic tasks, and wherein the vagus nerve stimulation pulse train is not presented between performances of the selected therapeutic task.

2. The method of claim 1 , wherein the pulse trains are about 500 milliseconds in duration.

3. The method of claim 1 , wherein the pulse trains have an amplitude of about 0.8 milliamperes.

4. The method of claim 1 , wherein a therapeutic task level is selected for each therapeutic task and the therapeutic task level may be changed between the repetitive performances.

5. A method of improving motor deficits in a stroke patient, comprising:

assessing a stroke patient's motor deficits;

determining therapeutic goals for the patient, based on the patient's motor deficits;

selecting a therapeutic task based on the therapeutic goals;

detecting motion during repetitive performances by the patient of the selected therapeutic task;

automatically stimulating a vagus nerve of the patient with an implanted neurostimulator that delivers pulse trains of electrical stimulation energy to the vagus nerve when a predetermined motion is detected;

ending the stimulation of the vagus nerve so that there is no stimulation between the performances; and

improving the patient's motor deficits,

wherein the action of stimulating the vagus nerve of the patient further comprises determining respective beginnings of performances of the selected therapeutic task, and applying the pulse trains to the vagus nerve based on the determined beginnings of the performances, and

wherein the stimulation pulse trains begin after the beginning of the respective selected therapeutic tasks, wherein the vagus nerve stimulation pulse trains end prior to the end of the respective selected therapeutic tasks, and wherein the vagus nerve stimulation pulse train is not presented between performances of the selected therapeutic task.

6. The method of claim 5 , wherein the pulse trains are about 500 milliseconds in duration.

7. The method of claim 5 , wherein the pulse trains have an amplitude of about 0.8 milliamperes.

8. The method of claim 5 , wherein the motion is detected by detecting change in color of the object by a camera.

Assignments (5)

Continuity (13)