Multi-chamber rotating valve
A fluid delivery system having a rotating reservoir insert and a cartridge body. The rotating reservoir insert having a plurality of reservoirs in communication with ports on the external surface of the insert. The ports are positioned such that upon rotation the port is in-line with a fluid extracting device, such as a syringe, capable of extracting fluid from the reservoir.
1. A fluid processing system comprising:
a drive assembly with a longitudinal axis of rotation, the drive assembly comprising a circular contact surface at a first end of the drive assembly, the circular contact surface comprising a heater at a first radial position and a magnet at a second radial position;
a cartridge body disposed proximate the first end of the drive assembly and non-rotatably disposed on the circular contact surface, the cartridge body comprising an inner cylindrical surface, a syringe molding extending from an outer surface of the cartridge body, a syringe port in the syringe molding that connects the inner cylindrical surface to the outer surface, the inner cylindrical surface and the outer surface being opposite each other and parallel the longitudinal axis of rotation of the drive assembly; and
a reservoir insert rotatably disposed to the inner cylindrical surface and operatively connected to the drive assembly such that rotation of the drive assembly causes the reservoir insert to rotate within the cartridge body, wherein the reservoir insert comprises
a cylindrical sidewall with a plurality of fluid ports disposed on an outside surface thereof including reservoir fluid ports, a first through-channel fluid port and a second through-channel fluid port, each fluid port being a first distance from a bottom of the reservoir insert such that each fluid port may be selectively aligned with the syringe port, the cylindrical sidewall further comprising a plurality of relief ports disposed on the outside surface and above the plurality of fluid ports,
a plurality of reservoirs within a perimeter defined by the cylindrical sidewall, each one of the plurality of reservoirs being fluidly connected to one reservoir fluid port of the plurality of fluid ports and one relief port of the plurality of relief ports, and
a through channel extending along the bottom of the reservoir insert, the through channel being fluidly connected to the first through-channel fluid port and the second through-channel fluid port at respective ends of the through channel, the through channel being selectively positionable proximate the heater or the magnet by rotation of the reservoir insert such that contents of the through channel can experience heat from the heater or a magnetic field from the magnet.
2. The system as recited in claim 1 , wherein the plurality of relief ports are disposed above the bottom of the reservoir insert by a second distance that is greater than the first distance.
3. The system as recited in claim 1 , further comprising a worm drive operatively connected to the drive assembly by a worm gear such that the actuation of the worm drive causes the drive assembly to rotate about the longitudinal axis of rotation.
4. The system as recited in claim 1 , wherein the cartridge body further comprises a reaction chamber disposed on the outer surface of the cartridge body.
5. The system as recited in claim 4 , wherein the reaction chamber comprises a chip having biological microprobes, the chip forming a wall of the reaction chamber.
6. The system as recited in claim 1 , further comprising a plunger fluidly connected to the syringe port.
7. The system as recited in claim 6 , wherein the syringe port extends perpendicularly from the outer surface of the cartridge body such that the syringe port may be selectively aligned with one fluid port of the plurality of fluid ports.
8. The system as recited in claim 1 , further comprising a film seal to retain fluids within the plurality of reservoirs.
9. The system as recited in claim 1 , further comprising a temperature sensor disposed in the circular contact surface proximate the heater.
10. The system as recited in claim 1 , wherein the circular contact surface further comprises an ultrasonic disruptor at a central position, and the plurality of reservoirs further comprises at least one sample reservoir that is located directly above the ultrasonic disruptor.
11. The system as recited in claim 10 , further comprising a temperature sensor disposed in the circular contact surface proximate the heater.
12. The system as recited in claim 10 , wherein each one of the plurality of reservoirs is disposed above the circular contact surface.
13. The system of claim 11 , wherein the at least one sample reservoir contains a plurality of disrupting objects.
14. The system of claim 12 wherein the disrupting objects are glass beads.
15. The system as recited in claim 1 , wherein the circular contact surface further comprises an ultrasonic source at a central position, and the plurality of reservoirs further comprises at least one sample reservoir that is located directly above the ultrasonic source.