Automatic analyzer and operating method for same
View Patent ↗An automatic analyzer is free from limitations on layout of various mechanisms, and thus causing no bottlenecks, for example, in a space-saving design of the automatic analyzer. This invention includes a coaxial planar duplex arrangement of two dilution disks each with annularly disposed dilution cells, and the dilution disks A and B operate independently of each other. Various mechanisms (parent-sample sampling mechanism, diluent delivery mechanism, diluent/sample mixing mechanism, and diluted-sample sampling mechanism) used in a dilution process can each access the two dilution disks. The dilution process for a parent sample, executed on the dilution disks A and B, can be continuously conducted by providing a fixed delay in operational timing between the two dilution disks.
1. An automatic analyzer comprising:
a reaction disk with reaction cells arrayed thereon;
a dilution disk with dilution cells annularly arrayed thereon;
a dilution disk rotating mechanism for rotating said dilution disk;
a parent-sample sampling mechanism configured to pipette a parent sample into the dilution cells from a sample container receiving a sample;
a diluent delivery mechanism configured to deliver a liquid diluent to the dilution cells having the parent sample pipetted thereinto;
a mixing mechanism for mixing the parent sample and the diluent pipetted into the dilution cells;
a diluted-sample sampling mechanism configured to pipette a diluted sample created by mixing the parent sample and the diluent in the dilution cells into the reaction cells;
a diluted sample analysis device configured to analyze diluted samples; and
a controller configured to control the rotating mechanism for rotating said dilution disk, and to control an operation of the parent sample sampling mechanism, an operation of the diluent delivery mechanism, an operation of the mixing mechanism, and an operation of the diluted sample sampling mechanism to execute the operations at positions which are different from each other on the dilution disk, wherein the controller is configured to control the operations being executed successively by the parent sample sampling mechanism, the diluent delivery mechanism, the mixing mechanism, and the diluted sample sampling mechanism with respect to respective ones of said dilution cells on the dilution disk by temporarily stopping the rotating of the dilution disk rotating mechanism at the different positions, each of the operations being executed at a stop timing of the rotation of the dilution disk,
wherein the controller is further configured to control analysis of the diluted sample analysis device to analyze diluted samples such that after analysis of a diluted sample, the dilution disk holds the diluted sample for a time it takes for completion of confirming whether re-analysis is necessary, and such that if the re-analysis is necessary, the dilution disk rotates and after the dilution cell containing the diluted sample has been moved to a diluted-sample suction position, the diluted-sample sampling is repeated;
two dilution disks that are rotated concentrically about a common axis by the rotating mechanism for rotating said dilution disk and wherein the two dilution disks are arranged with the dilution cells in two rows, one said row to form an inner peripheral region and an other said row to form an outer peripheral region,
wherein the controller is further configured to control the rotation of the rotating mechanism for rotating said two dilution disks such that while said one dilution disk is being used for pipetting the diluted sample, the other dilution disk is used to execute said operations for parent-sample, diluent delivery, and diluent/sample mixing sequentially, and such that after the pipetting of the diluted sample using the said one dilution disk, the diluted sample is immediately pipetted from the other dilution disk.
2. The automatic analyzer according to claim 1 , wherein the controller is further configured to
control the diluted sample analysis device such that for an analytical item requiring analysis, after the diluted sample has been left intact in the dilution cell for a fixed time, the pipetting of the diluted sample is skipped for a fixed time and a next dilution process is preferentially conducted, and
control the rotating mechanism for rotating said dilution disk such that after a lapse of a predetermined time, the dilution disk is rotated, and the dilution cell containing the diluted sample is moved to the diluted-sample suction position, and the diluted-sample sampling operation is executed.