IP Library Granted Patent US 8,784,803
Granted Patent B2
US 8,784,803 · App. 13/393,023 · Granted Jul 22, 2014

Therapeutic agent for liver-related diseases

Inventor: Akifumi Matsuyama (Kobe, JP)
Assignee: Osaka Air Machine Service, Ltd.
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Quick Facts
Patent No.
US 8,784,803
App. No.
13/393,023
Granted
Jul 22, 2014
Kind
B2
Abstract

The present invention relates to a therapeutic agent for liver-related diseases, comprising adipose tissue-derived multilineage progenitor cells; and others.

Claims (10)

1. A method for treating a liver-related disease, comprising:

administering adipose tissue-derived multilineage progenitor cells to a subject,

wherein the adipose tissue-derived multilineage progenitor cells are a population of cells obtained by:

(a) removing erythrocytes from a population of adipose tissue-derived cells, thereby to form a population of preadipose tissue-derived multilineage progenitor cells;

(b) culturing the resultant population of the preadipose tissue-derived multilineage progenitor cells;

(c) removing cells other than the adipose tissue-derived multilineage progenitor cells using ethylenediaminetetraacetic acid (EDTA) and without using trypsin.

2. The method according to claim 1 , wherein adipose tissue-derived multilineage progenitor cells are administered via portal vein.

3. The method according to claim 1 , wherein the liver-related disease is non-inflammatory.

4. The method according to claim 3 , wherein the liver-related disease is hemophilia or familial hypercholesterolemia.

5. The method according to claim 1 , wherein the liver-related disease is selected from blood coagulation disorders, metabolic diseases, and liver diseases.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 21, 2024
From: OSAKA AIR MACHINE SERVICE, LTD.
To: REGENE PHARM CO., LTD.
Reel/Frame 066851/0910 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 19, 2012
From: FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATION
To: OSAKA AIR MACHINE SERVICE, LTD.
Reel/Frame 029497/0513 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2012
From: MATSUYAMA, AKIFUMI
To: FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATION
Reel/Frame 027776/0126 →
Priority Claims (1)
JP 2009-198166 · Aug 28, 2009 · national
Continuity (1)
Related Publication 20120156181A1 · Jun 21, 2012