IP Library Granted Patent US 8,798,933
Granted Patent B2
US 8,798,933 · App. 12/586,075 · Granted Aug 5, 2014

Frozen compositions and methods for piercing a substrate

Inventors: Edward S. Boyden (Cambridge, MA); Daniel B. Cook (Seattle, WA); Roderick A. Hyde (Redmond, WA); Eric C. Leuthardt (St. Louis, MO); Nathan P. Myhrvold (Bellevue, WA); Elizabeth A. Sweeney (Seattle, WA); Lowell L. Wood, Jr. (Bellevue, WA)
Assignee: The Invention Science Fund I, LLC
G06F19/3456A61K9/1641A61K31/00A61K9/209A61K31/70A61K31/74A61K39/145C07K16/283A61K2039/505G06F19/3437A61K9/2866C07K16/2878A61K38/4833A61K9/143C07K16/2842A61K9/2095A61K9/0019A61K9/12A61M37/0015A61K9/08C07K16/30A61K9/1664A61K9/007A61K33/00A61K31/337A61K9/1688A61K9/0021A61K9/19A61M2037/0023A61M2037/003A61K38/38A61K38/4886A61K9/1611A61M2205/02C07K16/22C12N2760/16034A61K31/7088A61K2039/54A61K41/0004A61K39/00A61K45/06
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Quick Facts
Patent No.
US 8,798,933
App. No.
12/586,075
Granted
Aug 5, 2014
Kind
B2
Abstract

Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Claims (42)

1. A system comprising:

circuitry for accepting a first input associated with at least one parameter for making at least one frozen ice piercing implement;

circuitry for accepting a second input associated with at least one parameter for administering the at least one frozen ice piercing implement to at least one substrate, wherein the frozen ice piercing implement consists essentially of frozen ice and contains at least one detection material;

circuitry for processing the first input and the second input; and

circuitry for generating an output to a user readable display.

2. The system of claim 1 , further including circuitry for accepting a third input associated with at least one feature of the at least one subject.

3. The system of claim 1 , further including a transmitter for transmitting one or more signals that include information related to the processing of the first input and the second input.

4. The system of claim 1 , further including circuitry for making or administering at least one frozen ice piercing implement.

5. The system of claim 1 , further including circuitry for evaluating the at least one substrate for one or more indicators related to at least one parameter for administering the at least one frozen ice piercing implement.

6. A system comprising:

circuitry for receiving one or more signals that include information related to accepting input associated with at least one parameter for making or administering at least one frozen ice piercing implement to at least one substrate, the frozen ice piercing implement consisting essentially of frozen ice and including at least one therapeutic agent, adhesive agent, or biological remodeling agent and at least one detection material;

circuitry for receiving one or more signals that include information related to evaluating the at least one substrate for one or more indicators of administration of the at least one frozen ice piercing implement, or agent therefrom;

circuitry for processing the information related to the input associated with at least one parameter for making or administering the at least one frozen ice piercing implement to at least one substrate and the information related to the evaluating the at least one substrate; and

circuitry for generating an output to a user readable display.

7. The system of claim 6 , wherein the circuitry for receiving one or more signals includes circuitry for receiving one or more signals associated with selection of at least one parameter for making the at least one frozen ice piercing implement.

8. The system of claim 6 , wherein the output includes one or more instructions for making the at least one frozen ice piercing implement.

9. A system comprising:

circuitry for accepting a first input associated with at least one parameter for making at least one frozen ice piercing implement device, wherein the frozen ice piercing implement device consists essentially of frozen ice and contains at least one therapeutic agent, at least one adhesive agent, or at least biological remodeling agent, and includes at least one of a frozen ice piercing implement fluidic device or frozen ice piercing implement injection device;

circuitry for accepting a second input associated with at least one parameter for administering the at least one frozen ice piercing implement device to at least one substrate;

circuitry for processing the first input and the second input; and

circuitry for generating an output to a user readable display.

10. The system of claim 9 , wherein the frozen ice piercing implement injection device includes a frozen ice piercing implement auto-injection device.

11. The system of claim 9 , wherein the circuitry for processing the first input and the second input includes circuitry for electronically processing the first input and the second input.

12. The system of claim 9 , wherein the circuitry for processing the first input and the second input includes circuitry for electronically processing the first input and the second input by utilizing one or more of Gaussian smoothing, scaling, homomorphic filtering, parametric estimation techniques, Boolean operations, Monte Carlo simulations, wavelet based techniques, mirroring, smoothing, gradient weighted partial differential equation smoothing, NURBS, polygonal modeling, splines and patches modeling, algorithmic execution, logical decision-making, result prediction, Finite Element Analysis, or modification of a CAD design.

13. The system of claim 9 , further including circuitry for accepting a third input associated with at least one feature of the at least one subject.

14. The system of claim 9 , further including a transmitter for transmitting one or more signals that include information related to the means for processing the first input and the second input.

15. The system of claim 9 , further including circuitry for making or administering at least one frozen ice piercing implement device.

16. The system of claim 9 , further including circuitry for evaluating the at least one substrate for one or more indicators related to at least one parameter for administering the at least one frozen ice piercing implement device.

17. The system of claim 9 , further including a transmitter for transmitting one or more signals that include information relating to the accepting a first input or a second input and information related to the evaluating the at least one substrate.

18. A system comprising:

circuitry for receiving one or more signals that include information related to accepting input associated with at least one parameter for making or administering at least one frozen ice piercing implement, or frozen ice piercing implement device to at least one substrate;

wherein the at least one frozen ice piercing implement or frozen ice piercing implement device includes at least one agent and at least one detection material;

circuitry for receiving one or more signals that include information related to evaluating the at least one substrate for one or more indicators of administration of at least one frozen ice piercing implement device or agent therefrom;

circuitry for processing the information related to the input associated with at least one parameter for making or administering the at least one frozen ice piercing implement device to at least one substrate and the information related to the evaluating the at least one substrate; and

circuitry for generating an output to a user readable display.

19. The system of claim 18 , wherein the at least one frozen ice piercing implement device includes at least one of a frozen ice piercing implement device, frozen ice piercing implement fluidic device, or frozen ice piercing implement injection device.

20. The system of claim 18 , wherein the output includes one or more instructions for making the at least one frozen ice piercing implement, or frozen ice piercing implement device.

21. A system comprising:

circuitry for accepting a first input associated with at least one parameter for making at least one frozen ice piercing implement;

circuitry for accepting a second input associated with at least one parameter for administering the at least one frozen ice piercing implement to at least one substrate, wherein the frozen ice piercing implement consists essentially of frozen ice and contains at least one therapeutic agent, adhesive agent, or biological remodeling agent;

circuitry for processing the first input and the second input; and

circuitry for generating an output to a user readable display.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2016
From: THE INVENTION SCIENCE FUND I LLC
To: GEARBOX, LLC
Reel/Frame 037540/0396 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 10, 2014
From: SEARETE LLC
To: THE INVENTION SCIENCE FUND I, LLC
Reel/Frame 033069/0880 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 7, 2009
From: BOYDEN, EDWARD S.; COOK, DANIEL B.; HYDE, RODERICK A.; LEUTHARDT, ERIC C.; MYHRVOLD, NATHAN P.; SWEENEY, ELIZABETH A.; WOOD, JR., LOWELL L.
To: SEARETE LLC
Reel/Frame 023614/0355 →
Continuity (38)
Continuation In Part 12290671 · Oct 31, 2008
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Related Publication 20100114348A1 · May 6, 2010