Topical foam composition
The present invention relates to a novel oil in water emulsion aerosol foam composition containing an active agent for the treatment of various chronic and acute skin conditions, particularly acne and psoriasis; and processes for preparing the emulsion aerosol foam compositions. In particular, the present invention relates to oil in water emulsion aerosol foam compositions containing a retinoid in the oil phase.
1. An oil in water emulsion aerosol foam composition comprising an oil phase and a water phase, said composition containing an aerosol base comprising:
butylated hydroxytoluene
about 0.1%
ceteareth 12
about 5%
light mineral oil
about 6%
sorbic acid
about 0.4%
diisopropyl adipate
about 5%
tazarotene
about 0.1%
citric acid
about 0.03%
potassium citrate
about 0.57%
water
about 82.80%
wherein all percentages are expressed by weight and are based on the total weight of the aerosol base;
and a hydrocarbon propellant present in an amount from about 7 to about 8 grams per 100 grams of aerosol base.
2. An oil in water emulsion aerosol foam composition comprising an oil phase and a water phase, said composition containing an aerosol base comprising:
butylated hydroxytoluene
about 0.1%
ceteareth 12
about 5%
light mineral oil
about 6%
sorbic acid
about 0.15%
potassium sorbate
about 0.2%
diisopropyl adipate
about 5%
tazarotene
about 0.1%
citric acid
about 0.037%
potassium citrate
about 0.103%
water
about 83.31%
wherein all percentages are expressed by weight and are based on the total weight of the aerosol base;
and a hydrocarbon propellant present in an amount from about 7 to about 8 grams per 100 grams of aerosol base.
3. An oil in water emulsion aerosol foam composition comprising an oil phase and a water phase, said composition containing an aerosol base comprising:
butylated hydroxytoluene
about 0.1%
ceteareth 12
about 5%
light mineral oil
about 8%
sorbic acid
about 0.40%
diisopropyl adipate
about 7%
tazarotene
about 0.1%
citric acid
about 0.03%
potassium citrate
about 0.54%
water
about 78.83%
wherein all percentages are expressed by weight and are based on the total weight of the aerosol base;
and a hydrocarbon propellant present in an amount from about 7 to about 8 grams per 100 grams of aerosol base.