IP Library › Granted Patent US 8,822,500
Granted Patent B2
US 8,822,500 · App. 13/231,797 · Granted Sep 2, 2014

Tyrosine kinase inhibitors

Inventor: Vlad Edward Gregor (Del Mar, CA)
Assignee: Chembridge Corporation
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Quick Facts
Patent No.
US 8,822,500
App. No.
13/231,797
Granted
Sep 2, 2014
Kind
B2
Abstract

The present disclosure relates to the field of tyrosine kinase enzyme inhibition, in particular anaplastic lymphoma kinase (ALK) inhibition using novel small molecules. Provided are compounds capable to modulate ALK activity, compositions that comprise the compounds, and methods of using the compounds for the treatment or prevention of diseases or conditions that are characterized by ALK activity or expression.

Claims (2)

1. A compound represented by the structure of formula (45) or its stereoisomer, tautomer, pharmaceutically acceptable salt, or any combination thereof:

2. A pharmaceutical composition comprising a compound of claim 1 and one or more pharmaceutically acceptable diluents, excipients or carriers.

Continuity (4)
Continuation In Part 12922891
Provisional Application 61038032 · Mar 19, 2008
Provisional Application 61382485 · Sep 13, 2010
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