IP Library › Granted Patent US 8,871,771
Granted Patent B2
US 8,871,771 · App. 13/861,804 · Granted Oct 28, 2014

Salts of prodrugs of piperazine and substituted piperidine antiviral agents

Inventors: Yasutsugu Ueda (Clinton, CT); Timothy P. Connolly (Portland, CT); John F. Kadow (Wallingford, CT); Nicholas A. Meanwell (East Hampton, CT); Tao Wang (Farmington, CT); Chung-Pin H. Chen (Madison, CT); Kap-Sun Yeung (Madison, CT); Zhongxing Zhang (Madison, CT); David Kenneth Leahy (Hightstown, NJ); Shawn K. Pack (Lawrenceville, NJ); Nachimuthu Soundararajan (Kendall Park, NJ); Pierre Sirard (St. Jean sur Richelieu, CA); Kathia Levesque (St. Jean sur Richelieu, CA); Dominique Thoraval (Ville St. Laurent, CA)
Assignee: Bristol-Myers Squibb Company
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,871,771
App. No.
13/861,804
Granted
Oct 28, 2014
Kind
B2
Abstract

This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. wherein: X is C or N with the proviso that when X is N, R 1 does not exist; W is C or N with the proviso that when W is N, R 2 does not exist; V is C; E is hydrogen or a pharmaceutically acceptable salt thereof; and Y is selected from the group consisting of Also, this invention provides for intermediate Compounds II useful in making prodrug Compounds I. wherein: L and M are independently selected from the group consisting of C 1 -C 6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy.

Claims (1)

1. The compound, IIc, having the following structure:

Assignments (2)
CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY DATA PREVIOUSLY RECORDED AT REEL: 039323 FRAME: 0811. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Sep 8, 2016
From: BRISTOL-MYERS SQUIBB COMPANY
To: VIIV HEALTHCARE UK (NO. 4) LIMITED
Reel/Frame 039944/0582 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2016
From: BRISTOL-MYERS SQUIBB COMPANY
To: VIIV HEALTHCARE (NO. 4) LIMITED
Reel/Frame 039323/0811 →
Continuity (6)
Continuation 13429838 · Mar 26, 2012
Continuation 12767222 · Apr 26, 2010
Continuation 11066745 · Feb 25, 2005
Provisional Application 60635231 · Dec 10, 2004
Provisional Application 60553320 · Mar 15, 2004
Related Publication 20130253196A1 · Sep 26, 2013