IP Library Granted Patent US 8,883,780
Granted Patent B2
US 8,883,780 · App. 13/265,599 · Granted Nov 11, 2014

Crystal of a benzoxazinone compound

Inventor: Edwin Aret (Amsterdam, NL)
Assignee: Norgine B.V.
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Quick Facts
Patent No.
US 8,883,780
App. No.
13/265,599
Granted
Nov 11, 2014
Kind
B2
Abstract

Disclosed is a crystal of 2-(hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one useful as a preventive or therapeutic agent for obesity and the like. Specifically disclosed is a crystal of 2-(hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one having a powder X-ray diffraction pattern in which characteristic peaks appear at powder X-ray diffraction interplanar spacings (d) of around 16.54±0.2, 13.26±0.2, 4.70±0.2, 4.38±0.2, and 3.67±0.2λ.

Claims (3)

1. A crystal of 2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one having a powder X-ray diffraction pattern in which characteristic peaks appear at powder X-ray diffraction interplanar spacings (d) of around 16.54±0.2, 13.26±0.2, 4.70±0.2, 4.38±0.2 and 3.67±0.2 angstroms.

2. A solid pharmaceutical composition comprising the crystal of claim 1 and a pharmacologically acceptable carrier.

3. A method for treating obesity comprising administering an effective amount of the pharmaceutical composition of claim 2 to an individual in need thereof.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 1, 2011
From: TAKEDA PHARMACEUTICAL COMPANY LIMITED
To: NORGINE B.V.
Reel/Frame 027308/0167 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 21, 2011
From: ARET, EDWIN
To: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Reel/Frame 027101/0223 →
Priority Claims (1)
JP 2009-106606 · Apr 24, 2009 · national
Continuity (1)
Related Publication 20120101090A1 · Apr 26, 2012