Imaging method for motion analysis

1. A method for determining motion, relative position or deformation of an object or of at least two elements of an associated patient in order to synchronize a physiological condition perceived by the associated patient with a 2D data set, the method comprising:

obtaining a 3D image data set of the object or the at least two elements when the associated patient is in a first shape, first absolute position, or first relative position;

moving at least one of the elements and/or deforming the object of the associated patient to a second shape, second absolute position, or second relative position, different from the first shape, first absolute position, or first relative position;

selectively obtaining the 2D data set of the object or the at least two elements while in the second shape, second absolute position, or second relative position, wherein the 2D data set corresponds to the physiological condition perceived by the associated patient;

calculating a 3D image data set of the object or the at least two elements in the second shape, absolute, or relative position using said 2D image data set and said 3D image data set: and

determining the motion, relative position or deformation of the object based on a comparison of the calculated 3D image data set with the obtained 3D image data set.

2. The method according to claim 1 , further comprising segmenting the 3D image data set to determine the shapes and/or boundaries of the at least two elements.

3. The method according to claim 1 , wherein the 3D image data set is obtained from a CT-scan, MR-scan, 3D fluoroscopy, or 3D Ultrasound.

4. The method according to claim 1 , wherein the 2D image data set is obtained from a scout view obtained using a CT-scanner or MR-scanner, or from fluoroscopy or radiographs.

5. The method according to claim 1 , wherein the 2D image data set is obtained using the same imaging modality used to obtain the 3D image data set.

6. The method according to claim 1 , further comprising calibrating the 2D image data set to obtain projection parameters.

7. The method according to claim 1 , wherein moving at least one of the elements and/or deforming the object to have the second shape, second absolute position, or second relative position is performed using a deforming device.

8. The method according to claim 7 , wherein the deforming device comprises an inflatable cushion.

9. A computer program embodied on a non-transitory computer readable medium for determining motion, relative position or deformation of at least two elements of an associated patient in order to synchronize a physiological condition perceived by the associated patient with a 2D data set, comprising:

code for obtaining a 3D image data set of the object or the at least two elements when the associated patient is in a first shape, first absolute position, or first relative position;

code for selectively obtaining the 2D data set of the object or the at least two elements while in a second shape, second absolute position, or second relative position, different from the first shape, first absolute position, or first relative position, wherein the 2D data set corresponds to the physiological condition perceived by the associated patient;

code for calculating a 3D image data set of the object or the at least two elements in the second shape, absolute, or relative position using said 2D image data set and said 3D image data set: and

code that determines the motion, relative position or deformation of the object based on a comparison of the calculated 3D image data set with the obtained 3D image data set.

10. A system for determining motion, relative position or deformation of an object or of at least two elements of an associated patient in order to synchronize a physiological condition perceived by the associated patient with a 2D data set, comprising:

an apparatus for generating a 3D image data set of an object or elements or a data reading device to read previously recorded a 3D image data set of an object or elements of the associated patient;

an apparatus for generating at least one 2D image data set of the object or elements or a reading device to read data of at least one previously recorded 2D image data set of the object or elements;

a computer operatively coupled to receive said 3D image data set of an object or elements and said 2D image data set of the object or elements, said computer comprising:

a processor and memory, and

logic stored in the memory and executable by the processor, said logic including:

logic that obtains a 3D image data set of the object or the at least two elements when the associated patient is in a first shape, first absolute position, or first relative position;

logic that selectively obtains the 2D data set of the object or the at least two elements while in the second shape, second absolute position, or second relative position, different from the first shape, first absolute position, or first relative position, wherein the 2D data set corresponds to the physiological condition perceived by the associated patient;

logic that calculates a 3D image data set of the object or the at least two elements in the second shape, absolute, or relative position using said 2D image data set and said 3D image data set; and

logic that determines the motion, relative position or deformation of the object based on a comparison of the calculated 3D image data set to the obtained 3D image data set.

11. The system according to claim 10 , further comprising a deforming device for moving at least one of the elements and/or deforming the object from the first shape, first absolute position, or first relative position to the second shape, second absolute position, or second relative position.