Amide dendrimer compositions
Amide compounds, amide polymers, compositions including amide compounds and amide polymers may be used to bind target ions, such as phosphorous-containing compounds in the gastrointestinal tract of animals. In some cases, amide compounds and amide polymers may include a core derived from an amide polyol and an organic polyacid or ester.
1. A pharmaceutical composition comprising
a) an amide compound represented by the following Formula V:
wherein
R 3 is independently represented by the following Formula II:
wherein
p, q and r independently represent an integer from 0-2;
R 4 independently represents
wherein
m independently represents an integer from 1-20;
R 5 independently represents a hydrogen radical; a substituted or un-substituted alkyl radical; a substituted or un-substituted aryl radical; or R 5 and a neighboring R 5 together represent a link or links comprising a residue of a crosslinking agent, a substituted or un-substituted alicyclic radical, a substituted or un-substituted aromatic radical, or a substituted or un-substituted heterocyclic radical; or R 5 represents a link with another compound;
b) a crosslinking agent or residue thereof; and
c) a pharmaceutically acceptable excipient.
2. A pharmaceutical composition comprising
a) an amide compound represented by the following Formula VI:
b) a crosslinking agent or residue thereof; and
c) a pharmaceutically acceptable excipient.